Table III.
Ranges for Common Situation-Specific Inputs by Setting Tiers, Showing Assumed Tiers for the Nine Modeled Situations
Tier | Situations | a | Per-dose take rateb (tr) |
|||||||
---|---|---|---|---|---|---|---|---|---|---|
tOPV1 | tOPV2 | tOPV3 | mOPV1 | mOPV2 | mOPV3 | bOPV1 | bOPV3 | |||
| ||||||||||
High | The Netherlands, USA | 3–6 | 0.60–0.75 | 0.70–0.85 | 0.50–0.70 | 0.85–0.98 | 0.9–0.99 | 0.80–0.95 | 0.80–0.95 | 0.80–0.95 |
Medium | Albania,c Cuba, Haiti, Madura, northern Nigeria, Tajikistan | 6–11 | 0.35–0.50 | 0.60–0.75 | 0.30–0.45 | 0.60–0.75 | 0.60–0.75 | 0.60–0.75 | 0.50–0.65 | 0.45–0.60 |
Low | Northern India | 10–14 | 0.25–0.40 | 0.50–0.65 | 0.20–0.35 | 0.40–0.60 | 0.40–0.60 | 0.35–0.55 | 0.40–0.60 | 0.30–0.50 |
Acronyms: bOPV1,3 = type 1 or 3 component of bivalent oral poliovirus vaccine, respectively; mOPV1,2,3 = monovalent oral poliovirus vaccine type 1, 2, or 3, respectively; R0 = basic reproductive number; tOPV1,2,3 = type 1, 2, or 3 component of trivalent oral poliovirus vaccine, respectively; USA = United States of America
Based on existing estimates(9,10,13,26,31,53,54) and adjusted somewhat downward compared to prior work(9,10,13) due to updated characterization of immunity states and waning.
Use low-tier take rates during times of major cold chain issues.