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. Author manuscript; available in PMC: 2025 Jan 4.
Published in final edited form as: Risk Anal. 2013 Mar 22;33(4):703–749. doi: 10.1111/risa.12044

Table III.

Ranges for Common Situation-Specific Inputs by Setting Tiers, Showing Assumed Tiers for the Nine Modeled Situations

Tier Situations R0 a Per-dose take rateb (tr)
tOPV1 tOPV2 tOPV3 mOPV1 mOPV2 mOPV3 bOPV1 bOPV3

High The Netherlands, USA 3–6 0.60–0.75 0.70–0.85 0.50–0.70 0.85–0.98 0.9–0.99 0.80–0.95 0.80–0.95 0.80–0.95
Medium Albania,c Cuba, Haiti, Madura, northern Nigeria, Tajikistan 6–11 0.35–0.50 0.60–0.75 0.30–0.45 0.60–0.75 0.60–0.75 0.60–0.75 0.50–0.65 0.45–0.60
Low Northern India 10–14 0.25–0.40 0.50–0.65 0.20–0.35 0.40–0.60 0.40–0.60 0.35–0.55 0.40–0.60 0.30–0.50

Acronyms: bOPV1,3 = type 1 or 3 component of bivalent oral poliovirus vaccine, respectively; mOPV1,2,3 = monovalent oral poliovirus vaccine type 1, 2, or 3, respectively; R0 = basic reproductive number; tOPV1,2,3 = type 1, 2, or 3 component of trivalent oral poliovirus vaccine, respectively; USA = United States of America

a

Based on existing estimates(9,10,13,26,31,53,54) and adjusted somewhat downward compared to prior work(9,10,13) due to updated characterization of immunity states and waning.

b

Based on reviews of seroconversion studies in Thompson et al.(6) and Cáceres and Sutter.(52)

c

Use low-tier take rates during times of major cold chain issues.