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. 2025 Jan 4;15:765. doi: 10.1038/s41598-025-85468-3

Table 2.

Sarcopenia and its components in male and female participants stratified by serum 25(OH)D levels.

Males
(n = 211)
Females
(n = 157)
Q1 (n = 73) Q2 (n = 68) Q3 (n = 70) P value Q1 (n = 52) Q2 (n = 53) Q3 (n = 52) P value
Calf circumference (cm) 34.35 ± 3.40 34.40 ± 3.13 34.61 ± 3.22 0.966 34.54 ± 2.83 33.11 ± 3.39 33.68 ± 3.13 0.048
HGS (kg) 29.20 ± 6.81 29.48 ± 7.27 28.03 ± 6.49 0.356 22.76 ± 4.70 21.80 ± 4.05 23.46 ± 5.92 0.404
Low HGS (%) 29 (39.7) 28 (41.2) 37 (52.9) 0.228 7 (13.5) 14 (26.4) 8 (15.4) 0.181
SMI (kg/m2) 7.36 ± 0.67 7.47 ± 0.74 7.41 ± 0.73 0.657 6.53 ± 1.28 6.78 ± 1.07 6.82 ± 1.19 0.467
6-meter gait speed (m/s) 1.04 ± 0.21 1.06 ± 0.17 1.07 ± 0.19 0.617 0.96 ± 0.20 0.96 ± 0.22 1.03 ± 0.22 0.234
Time to complete 5 sit-to-stand movements (s) 15.95 ± 3.22 15.43 ± 3.91 16.33 ± 5.71 0.534 16.41 ± 3.89 16.06 ± 3.37 15.98 ± 2.67 0.986
SPPB ≤ 9 points (n, %) 22 (30.1) 16 (23.5) 23 (32.9) 0.463 29 (55.8) 24 (45.3) 29 (55.8) 0.461
Sarcopenia (%) 22 (30.1) 18 (26.5) 22 (31.4) 0.803 8 (15.4) 3 (5.7) 6 (11.5) 0.271

Male participants were divided into Q1 group (25(OH)D ≤ 35.80 ng/ml, n = 73), Q2 group (35.80 ng/ml < 25(OH)D ≤ 45.52 ng/ml, n = 68) and Q3 group (25(OH)D > 45.52 ng/ml, n = 70). Female participants were divided into Q1 group (25(OH)D ≤ 24.72 ng/ml, n = 52), Q2 group (24.72 ng/ml < 25(OH)D ≤ 30.94 ng/ml, n = 53) and Q3 group (25(OH)D > 30.94 ng/ml, n = 52).

Q, quartile; 25(OH)D, 25-hydroxyvitamin D; HGS, handgrip strength; SMI, skeletal muscle index; SPPB, Short Physical Performance Battery.