Table 2.
Comparisons of myocardial mechanics according to patterns of left ventricular fibrosis.
| None (n = 41) |
Mid-epicardial LGE (n = 73) |
Subendocardial LGE (n = 19) |
p | |
|---|---|---|---|---|
| Maximal thickness, mm | 17.3 ± 2.8 | 19.9 ± 3.9* | 18.2 ± 3.0 | < 0.001 |
| E/e′ | 12.6 ± 4.7 | 16.3 ± 6.5* | 14.3 ± 6.0 | 0.005 |
| LV mass index by CMR, g/m2 | 73.1 ± 15.5 | 91.6 ± 23.3* | 85.7 ± 22.9‡ | < 0.001 |
| Average anteroseptal wall thickness, mm | 10.2 ± 2.4 | 13.1 ± 3.3* | 12.3 ± 2.3‡ | < 0.001 |
| Average lateral wall thickness, mm | 8.1 ± 2.0 | 8.0 ± 2.1† | 9.9 ± 2.6 ‡ | 0.003 |
| Average apical wall thickness, mm | 10.1 ± 4.0 | 10.4 ± 3.2 | 12.6 ± 4.2 | 0.038 |
| LV mechanics | ||||
| LV EF, % | 65.6 ± 7.4 | 63.9 ± 11.3 | 66.2 ± 7.4 | 0.543 |
| LV GLSmyo, % | − 17.4 ± 3.8 | − 15.4 ± 4.5* | − 15.2 ± 3.7 | 0.043 |
| Anteroseptal LS, % | − 17.9 ± 3.7 | − 15.2 ± 4.4* | − 17.6 ± 5.2 | 0.003 |
| Lateral LS, % | − 24.6 ± 5.0 | − 23.4 ± 6.4 | − 22.3 ± 5.1 | 0.312 |
| Apical LS, % | − 15.4 ± 5.6 | − 13.9 ± 5.7 | − 11.9 ± 3.7‡ | 0.070 |
| LV GLSendo, % | − 21.6 ± 4.2 | − 19.1 ± 5.7* | − 18.8 ± 4.7 | 0.032 |
| LV average CSmyo, % | − 20.64 ± 3.42 | − 18.89 ± 4.38* | − 19.53 ± 2.85 | 0.075 |
| Basal LV-CSmyo, % | − 20.62 ± 3.42 | − 18.97 ± 4.52* | − 19.54 ± 2.87 | 0.110 |
| Mid LV-CSmyo, % | − 20.67 ± 3.43 | − 18.84 ± 4.33* | − 19.58 ± 2.86 | 0.059 |
| Apical LV-CSmyo, % | − 20.64 ± 3.41 | − 18.85 ± 4.34* | − 19.49 ± 2.83 | 0.066 |
| Basal LV rotationmyo,° | − 3.6 ± 5.4 | − 5.5 ± 5.3 | − 3.4 ± 4.8 | 0.105 |
| Basal LV rotationendo,° | − 3.2 ± 9.7 | − 7.4 ± 9.1* | − 3.4 ± 7.7 | 0.040 |
| Apical LV rotationmyo,° | 6.6 ± 8.3 | 2.1 ± 8.3* | 6.0 ± 10.2 | 0.017 |
| Apical LV rotationendo,° | 17.0 ± 22.2 | 10.0 ± 20.3 | 14.5 ± 20.1 | 0.220 |
| Twistmyo,° | 10.2 ± 10.6 | 7.6 ± 9.8 | 9.4 ± 9.6 | 0.382 |
| Twistendo, ° | 20.2 ± 26.1 | 17.4 ± 23.6 | 17.9 ± 20.9 | 0.830 |
See abbreviations in Table 1; LS, longitudinal strain; *, ‡p < 0.05 vs. none group; †p < 0.05 vs. subendocardial LGE group.