Table 2.
Injection precision, linearity, and QL data from various solvent systems.
| Solvent System | Injection Precision (% RSDall of Standard Peak Area) | Correlation of Determination (R) | Slope (pA∗min.∗mL/mg) | Y-intercept (pA∗min.) | Std. Dev. of Residuals | Residual Sum of Squares | % RSD of RFs Across the Range | QL S/N at 0.5 μg/mL (Each Injection) | QL Injection Precision (% RSD6 of Peak Area) |
|---|---|---|---|---|---|---|---|---|---|
| 1 mM HCl in DMAc | 1.1 % | 1.0000 | 17.248 | −0.00047 | 0.00100 | 4.0 × 10−6 | 3.0 % | 17, 19, 19, 20, 19, 16 | 4.4 % |
| 1 mM HCL in DMF | 2.8 % | 1.0000 | 19.873 | −0.00097 | 0.00276 | 3.0 × 10−5 | 3.2 % | 19, 19, 21, 22, 22, 21 | 2.5 % |
| 1 mM HCl in DMI | 0.5 % | 0.9999 | 18.768 | 0.00132 | 0.00437 | 7.6 × 10−5 | 5.5 % | 19, 15, 20, 19, 20, 20 | 2.9 % |
| 1 mM HCl in NMP | 1.6 % | 1.0000 | 18.380 | 0.00010 | 0.00207 | 1.7 × 10−5 | 3.3 % | 15, 17, 12, 17, 14, 15 | 3.6 % |
| 1 mM HCl in Cyrene® | 5.7 % | 0.9988 | 9.611 | 0.01010 | 0.00889 | 3.2 × 10−4 | 22.7 % | 8, 13, 10, 10, 12, 12 |
5.8 % |
| 10 mM Tetrabutylammonium Chloride in DMAc | 0.8 % | 1.0000 | 17.294 | −0.00320 | 0.00241 | 2.3 × 10−5 | 1.0 % | 10, 11, 12, 11, 13, 11 | 5.8 % |