Table 4.

Toxicity Grade among Studied Groups and during Follow up

		Palbociclib N(%)		Ribociclib N(%)	P
Nausea No		40 (68.96)		33 (56.89)	0.35
GI-GII		16 (27.58)		23 (39.65)
GIII-GIV		2 (3.44)		2 (3.44)
Vomiting No		46 (79.31)		44 (75.86)	0.44
GI-GII		9 (15.51)		13 (22.41)
GIII-GIV		3 (5.17)		1 (1.72)
Constipation No		42 (72.41)		43 (74.13)
GI-GII		16 (27.58)		15 (25.86)
GIII-IV		0 (0)		0 (0)
Diarrhea No		47 (81.03)		48 (82.75)	1
GI-GII		9 (15.51)		9 (15.51)
GIII-GIV		2 (3.44)		1 (1.72)
Anemia No		29 (50)		32 (55.17)	0.83
GI-GII		24 (41.37)		22 (37.93)
GIII-GIV		5 (8.62)		4 (6.89)
Neutropenia No		28 (48.27)		32 (55.17)	0.71
GI-GII		19 (32.75)		15 (25.86)
GIII-GIV		11 (18.96)		11 (18.96)
Thrombocytopenia No		51(87.93)		56 (96.55)	0.1
GI-GII		1(1.72)		1 (1.72)
GIII-GIV		6(10.34)		1 (1.72)
High ALT No		52 (89.65)		53 (91.37)	0.75
GI-GII		6 (10.34)		5 (8.62)
GIII-GIV		0 (0)		0 (0)
High AST No		45 (77.58)		49 (84.48)	0.34
GI-GII		13 (22.41)		9 (15.51)
GIII-GIV		0 (0)		0 (0)
Fatigue No		31 (53.44)		30 (51.72)	0.91
GI-GII		23 (39.65)		22 (37.93)
GIII-GIV		4 (6.89)		6 (10.34)
Arthralgia No		50 (86.20)		46 (79.31)	0.44
GI-GII		8 (13.79)		10 (17.24)
GIII-GIV		0 (0)		2 (3.44)
Backache No		43(74.13)		44 (75.86)	1
GI-GII		14(24.13)		13 (22.41)
GIII-GIV		1(1.72)		1 (1.72)
Cough No		42 (72.41)		39 (67.24)	0.56
GI-GII		15 (25.86)		19 (32.75)
GIII-GIV		1 (1.72)		0 (0)
Headache No		40 (68.96)		39 (67.24)	1
GI-GII		18 (31.03)		18 (31.03)
GIII-GIV		0 (0)		1 (1.72)
Pruritis No		44 (75.86)		44 (75.86)	1
GI-GII		14 (24.13)		13 (22.41)
GIII-GIV		0 (0)		1 (1.72)
Rash				0.54
No	51 (87.93)	53 (91.37)
GI-GII	7 (12.06)	5 (8.62)
GIII-GIV	0 (0)	0 (0)
Alopecia				0.5
No	47 (81.03)	44 (75.86)
GI-GII	11 (18.96)	14 (24.13)
GIII-GIV	0 (0)	0 (0)
Long QT				1
No	57 (98.27)	56 (96.55)
GI-GII	1 (1.72)	1 (1.72)
GIII-GIV	0 (0)	1 (1.72)
Lung disease				0.76
No	52 (89.65)	51 (87.93)
GI-GII	6 (10.34)	7 (12.06)
GIII-GIV	0 (0)	0 (0)