Table 2.

COX Regression Analysis of the Prognostic Factors Associated with HER2-Positive MBC Patients.

Characteristics	Univariable OR (95% CI)"	P	Multivariable OR (95% CI)"	P
Race
Black	1 (reference)
Other	0.19 (0.02-1.44)	0.108
White	0.90 (0.46-1.75)	0.75
Age
<65	1 (reference)
≥65	1.44 (0.82-2.50)	0.202
Marital status
Married	1 (reference)
Unmarried	1.57 (0.91-2.72)	0.104
Grade
I	1 (reference)
II	0.18 (0.04-0.76)	0.02	1.08 (0.15 - 7.93)	0.94
III	0.14 (0.03-0.61)	0.009	1.05 (0.14 - 7.98)	0.962
Laterality
Left	1 (reference)
Right	0.63 (0.37-1.09)	0.1
T stage
T1	1 (reference)
T2	2.03 (1.00-4.14)	0.051	2.03 (0.96 - 4.33)	0.066
T3	6.41 (2.03-20.2)	0.002	2.29 (0.34 - 15.61)	0.398
T4	4.81 (2.15-10.74)	<0.001	4.19 (1.54 - 11.4)	0.005
N stage
N0	1 (reference)
N1	1.98 (1.08-3.62)	0.028	1.21 (0.59 - 2.49)	0.61
N2	1.93 (0.66-5.63)	0.231	2.10 (0.69 - 6.37)	0.19
N3	2.12 (0.9-5.01)	0.085	0.50 (0.14 - 1.78)	0.283
M stage
M0	1 (reference)
M1	6.57 (3.48-12.43)	<0.001	3.90 (1.27 - 11.92)	0.017
Tumor size
<50	1 (reference)
≥50	3.82 (1.79-8.15)	<0.001	1.25 (0.34 - 4.67)	0.738
ER
Negative	1 (reference)
Positive	1.95 (0.47-8.01)	0.355
PR
Negative	1 (reference)
Positive	1.49 (0.64-3.48)	0.36
Surgery
No	1 (reference)
Yes	0.19 (0.09-0.39)	<0.001	0.31 (0.12 - 0.84)	0.021
Radiation
No	1 (reference)
Yes	0.94 (0.5-1.75)	0.841
Chemotherapy
No	1 (reference)
Yes	0.52 (0.3-0.89)	0.018	0.39 (0.21 - 0.71)	<0.002