Table 2.
Clinical variables before and after surgery (N = 22).
Pre- surgical |
Post- surgical |
p | |
---|---|---|---|
Levodopa equivalent daily dose, mg | 1392 ± 500 | 963 ± 505 | < <0.001 |
MDS-UPDRS-III off med / off stim | 47.1 ± 14.4 | 44.3 ± 11.9a | 0.231 |
MDS-UPDRS-III off med / on stim | 24.8 ± 10.7b | < <0.001† | |
MDS-UPDRS-III on med / on stim | 19.8 ± 10.7 | 13.9 ± 8.6 | 0.004 |
MDS-UPDRS-III gait score on med / on stim | 0.5 ± 0.7 | 0.5 ± 0.6 | ≈ 1.0‡ |
All p values from paired t-tests calculated between pre-surgical and post-surgical except †paired t-test vs. pre-surgical off med; ‡Wilcoxon signed-rank test. aN = 20. bN = 19. Note: off stim and on stim refer to the post-surgical visit only; e.g., on med / on stim refers to on medication at the pre-surgical visit and on medications and on stimulation at the post-surgical visit.