Table 12.

Molecular docking data for Human Histamin H1 Receptor

Compounds	ΔG (kcal/mol)	H bond interaction	Hydrofobic Interaction	Electrostatic interaction
Desloratadine	− 7.2	–	VAL71, LEU149, TRP152
Levocetirizine	− 7.1	–	TYR158, PRO161, ILE197	–
Fexofenadine	− 8.9	–	PHE116, PHE119, ILE120, ILE123, ALA151, PRO202	–
CAPE	− 5.6	TYR210	LEU207, ALA211, TYR214	MET421
Quercetin	− 6.6	GLU181, TYR1850	TRP93, CYS100, ARG175, CYS180	ARG97
Melatonin	− 6.2	GLY164, TRP165, ASP183	VAL187, PHE190	–
Curcumin	− 6.1	TRP152	LEU149, TRP152, PHE153	–
Vitamin C	− 4.8	GLY164	–	–