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. 2024 Dec 6;16(12):e75206. doi: 10.7759/cureus.75206

Table 2. Summary of meta-analysis results.

PFS: progression-free survival, OS: Overall survival, ORR: overall response rate.

Analysis Therapy HR 95% CI Result
OS pembrolizumab 1.00 0.94-1.07 No statistically significant differences were observed between zolbetuximab and other inhibitors
sintilimab 0.99 0.89-1.09
sugemalimab 0.98 0.87-1.10
tislelizumab 0.97 0.87-1.09
zolbetuximab 0.98 0.91-1.07
nivolumab 1.00 -
PFS pembrolizumab 1.00 0.93-1.06 No statistically significant differences were observed between zolbetuximab and other inhibitors
sintilimab 0.91 0.83-1.00
sugemalimab 0.92 0.84-1.02
tislelizumab 0.93 0.84-1.03
zolbetuximab 0.96 0.88-1.05
nivolumab 1.00 -
ORR       All regimens presented similar effects on ORR