| Gut microbiome |
Ni et al. [23] |
30 vitiligo patients and 30 matched healthy
controls |
There was a characteristic lower Bacteroidetes:
Firmicutes ratio in individuals with vitiligo compared with healthy controls. |
|
Dellacecca et al. [58] |
10 mice untreated, 10 mice treated with ampicillin, 8
mice treated with neomycin |
Ampicillin treatment was associated with accelerated
depigmentation and reduced bacteria in fecal pellets. |
|
Luan et al. [59] |
25 patients with non-segmental vitiligo and 25 matched
healthy controls |
Compared with healthy controls, the alpha diversity of
intestinal microbiome in vitiligo patients was significantly reduced. |
|
Mao et al. [60] |
Number of single-nucleotide polymorphisms (SNPs) =
16,380,442; ncase = 131; ncontrol = 207,482 |
There was an association between disease duration and
Ruminococcus in vitiligo. |
|
|
Helicobacter
pylori(H. pylori) |
Doğan et al. [68] |
68 patients with vitiligo and 65 patients with telogen
effluvium (TE) |
The rates of H. pylori positivity,
H. pylori CagA, and IgG in serum in the vitiligo group were
significantly higher than in the TE group. |
| Bakry et al. [69] |
75 patients with non-segmental vitiligo and 75 healthy
people as a control group |
H. pylori infection was positive in
49 (65.3%) vitiligo cases compared with 18 (24%) in the control group
(***p=0.001). |
| Rifaioğlu et al. [70] |
34 patients with vitiligo and 30 matched healthy
controls |
The frequency of H. pylori infection
was higher in the patient with vitiligo than in the control (*p=0.012). |
