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. Author manuscript; available in PMC: 2025 Jan 26.
Published in final edited form as: Neuroscience. 2024 Nov 26;565:327–341. doi: 10.1016/j.neuroscience.2024.11.063

Table 1.

Neuronal types in respective TG mice LS neurons based on markers.

Parameters GAD Parvalbumin Somatostatin VIP
Input resistance (MΩ) 287 ± 30 447 ± 161 329 ± 40 845 ± 217
RMP (mV) −63 ± 2 −59 ± 3 −58 ± 3 −62 ± 5
Rheobase (pA) 54 ± 7 30 ± 6 26 ± 5 20 ± 0
Overshoot (mV) 39 ± 4 45 ± 8 44 ± 3 49 ± 5
Hyperpolarization (mV) −28 ± 3 −26 ± 3 −32 ± 4 −38 ± 8
Type III AP (n) 6 0 4 0
Temperature (°C) 24 ± 0.4 24 ± 0.8 22 ± 0.2 23 ± 1
Neuron n 10 4 – 5 9 3 – 6
Mice n 8 2 8 5
Female n 2 0 0 1
Age (Days) 144 ± 15 31 ± 2 40 ± 3 43 ± 2

The overshoot is estimated during 80-pA steps for GAD+ and PV+ neurons, while by 100 and 60 pA pulses in SOM+ and VIP+ cells, respectively. The magnitude of hyperpolarization is estimated upon – 100 pA. Note differences in age spans. Based on one-way ANOVA the P < 0.01 for values in bold.