Table 1.
Neuronal types in respective TG mice LS neurons based on markers.
| Parameters | GAD | Parvalbumin | Somatostatin | VIP |
|---|---|---|---|---|
| Input resistance (MΩ) | 287 ± 30 | 447 ± 161 | 329 ± 40 | 845 ± 217 |
| RMP (mV) | −63 ± 2 | −59 ± 3 | −58 ± 3 | −62 ± 5 |
| Rheobase (pA) | 54 ± 7 | 30 ± 6 | 26 ± 5 | 20 ± 0 |
| Overshoot (mV) | 39 ± 4 | 45 ± 8 | 44 ± 3 | 49 ± 5 |
| Hyperpolarization (mV) | −28 ± 3 | −26 ± 3 | −32 ± 4 | −38 ± 8 |
| Type III AP (n) | 6 | 0 | 4 | 0 |
| Temperature (°C) | 24 ± 0.4 | 24 ± 0.8 | 22 ± 0.2 | 23 ± 1 |
| Neuron n | 10 | 4 – 5 | 9 | 3 – 6 |
| Mice n | 8 | 2 | 8 | 5 |
| Female n | 2 | 0 | 0 | 1 |
| Age (Days) | 144 ± 15 | 31 ± 2 | 40 ± 3 | 43 ± 2 |
The overshoot is estimated during 80-pA steps for GAD+ and PV+ neurons, while by 100 and 60 pA pulses in SOM+ and VIP+ cells, respectively. The magnitude of hyperpolarization is estimated upon – 100 pA. Note differences in age spans. Based on one-way ANOVA the P < 0.01 for values in bold.