Table 3.
Univariable and multivariable logistic regression results considering hypoadrenocorticism as the dependent variable.
| Univariable logistic regression model | Multivariable logistic regression model | |||||||
|---|---|---|---|---|---|---|---|---|
| Variable | β | SE | OR (CI 95%) | p | β | SE | OR (CI 95%) | p |
| Male vs. Female | 0.59 | 0.46 | 1.81 (0.74–4.56) | 0.19 | – | – | – | – |
| Age (years) | 0.08 | 0.07 | 1.08 (0.95–1.23) | 0.24 | – | – | – | – |
| Weight (kg) | −0.03 | 0.02 | 0.97 (0.92–1.01) | 0.11 | – | – | – | – |
| Entire vs. Neutered | 1.06 | 0.49 | 2.89 (1.14–7.89) | 0.03 | – | – | – | – |
| Acute Gastrointestinal Signs (yes) | 2.10 | 0.52 | 8.19 (3.03–23.78) | <0.001 | – | – | – | – |
| Chronic gastrointestinal signs (yes) | −1.22 | 0.47 | 0.29 (0.11–0.73) | 0.009 | – | – | – | – |
| Neurological signs (yes) | −0.39 | 0.85 | 0.68 (0.09–3.18) | 0.65 | – | – | – | – |
| Polyuria/Polydipsia (yes) | 1.25 | 0.59 | 3.49 (1.09–11.79) | 0.04 | – | – | – | – |
| Lethargy (yes) | 2.55 | 0.54 | 12.83 (4.66–39.46) | <0.001 | 1.66 | 0.73 | 5.25 (1.26–23.36) | 0.02 |
| Anorexia (yes) | 1.76 | 0.49 | 5.78 (2.23–15.78) | <0.001 | 1.31 | 0.79 | 3.69 (0.78–18.75) | 0.09 |
| First gastrointestinal episodes (yes) | 1.62 | 0.75 | 5.04 (1.22–25.52) | 0.03 | – | – | – | – |
| Albumin | −1.13 | 0.49 | 0.32 (0.11–0.83) | 0.02 | −1.15 | 0.67 | 0.32 (0.08–1.16) | 0.09 |
| ALP | −3.79e-5 | 8.84e-4 | 0.99 (0.99–1.00) | 0.97 | – | – | – | – |
| ALT | 0.008 | 0.004 | 1.01 (1.00–1.02) | 0.04 | – | – | – | – |
| BUN | 0.06 | 0.02 | 1.07 (1.04–1.11) | <0.001 | – | – | – | – |
| Creatinine | 2.24 | 0.64 | 9.37 (3.13–39.03) | <0.001 | – | – | – | – |
| Eosinophil count | 7.03e-5 | 4.75e-4 | 1.00 (0.99–1.00) | 0.88 | – | – | – | – |
| Erythrocyte count | 0.35 | 0.19 | 1.42 (1.01–2.14) | 0.06 | – | – | – | – |
| Glucose | −0.003 | 0.008 | 0.99 (0.98–1.01) | 0.71 | – | – | – | – |
| GGT | 0.16 | 0.09 | 1.17 (1.01–1.42) | 0.08 | – | – | – | – |
| Haematocrit | 0.011 | 0.03 | 1.01 (0.96–1.07) | 0.68 | – | – | – | – |
| Leucocyte count | 0.08 | 0.04 | 1.08 (1.00–1.18) | 0.06 | – | – | – | – |
| Lymphocyte count | 0.0002 | 0.0001 | 1.00 (0.99–1.00) | 0.25 | – | – | – | – |
| Sodium/potassium ratio | −0.15 | 0.04 | 0.86 (0.79–0.93) | <0.001 | – | – | – | – |
| Neutrophil count | 8.58e-5 | 4.66e-5 | 1.00 (0.99–1.00) | 0.07 | – | – | – | – |
| Potassium | 0.74 | 0.23 | 2.09 (1.39–3.42) | 0.001 | – | – | – | – |
| Sodium | −0.21 | 0.05 | 0.81 (0.73–0.88) | <0.001 | −0.18 | 0.05 | 0.84 (0.74–0.91) | <0.001 |
β - regression coefficient; SE, standard error; OR, odds ratio: CI 95%, confidence interval at 95%. For clinical signs the reference category considered was 0 (negative response).