Table 5.
Sensitivity analysis of the association between SIRI and the risk of 30-day mortality in patients with ADHF.
| Hazard ratios (95% confidence interval) | ||||||
|---|---|---|---|---|---|---|
| Sensitivity-1 | Sensitivity-2 | Sensitivity-3 | Sensitivity-4 | Sensitivity-5 | Sensitivity-6 | |
| SIRI (Per SD increase) | 1.19 (1.01, 1.41) | 1.23 (1.01, 1.50) | 1.37 (1.10, 1.71) | 1.22 (1.08~1.37) | 1.19 (1.03, 1.37) | 1.17 (1.02, 1.34) |
| SIRI (tertiles) | ||||||
| T1(Low) | 1(ref) | 1(ref) | 1(ref) | 1(ref) | 1(ref) | 1(ref) |
| T2(Moderate) | 4.75 (0.57, 39.41) | 2.35 (0.23, 23.97) | inf. (0.00, Inf) | 2.27 (0.61~8.45) | 4.34 (0.45, 41.67) | 5.31 (0.63, 44.58) |
| T3(High) | 7.38 (0.92, 59.32) | 8.59 (1.02, 72.74) | inf. (0.00, Inf) | 4.74 (1.35~16.68) | 7.48 (0.84, 66.80) | 8.21 (1.03, 65.70) |
| P-trend | 0.0377 | 0.0126 | 0.0171 | 0.005 | 0.0433 | 0.0280 |
inf: Infinity; Sensitivity-1: based on model 3, with additional adjustments for the quadratic term of age; Sensitivity-2: excluding patients with three chronic diseases at baseline; Sensitivity-3: excluding deaths occurring within the first three days of follow-up; Sensitivity-4: missing values were estimated using the K-nearest neighbor interpolation method; Sensitivity-5: Patients with a history of chronic kidney disease, deep vein thrombosis, rheumatoid arthritis, and periodontitis were excluded; Sensitivity-6: Further adjustments were made for treatment factors including diuretic, ACEI/ARB/ARNI, beta-blockers, digitalis, SGTL-2.