Table 4.
Multivariate Cox proportional hazards analyses of the number of abnormal tumor markers on overall survival and recurrence free survival.
| Variables | Recurrence free survival | Overall survival | ||
|---|---|---|---|---|
| HR (95%Cl) | P value | HR (95%Cl) | P value | |
| Age | 1.01 (0.97-1.03) | 0.627 | 1.02 (0.98-1.06) | 0.383 |
| Male | 1.19 (0.63-2.25) | 0.594 | 0.97 (0.45-2.10) | 0.940 |
| ASA 3-4 | 2.05 (0.66-6.27) | 0.212 | 0.32 (0.04-2.78) | 0.301 |
| Increased tumor marker | 0.002 | 0.033 | ||
| 1 | 1.23 (0.58-2.63) | 0.590 | 1.99 (0.84-4.74) | 0.115 |
| 2 | 5.17 (1.37-19.45) | 0.015 | 4.18 (0.94-18.66) | 0.035 |
| 3 | 11.40 (2.77-46.97) | 0.001 | 4.59 (0.91-22.66) | 0.031 |
| pT3-4 | 2.48 (1.21-5.09) | 0.013 | 5.10 (2.16-12.04) | <0.001 |
| pN1-3 | 2.36 (1.17-4.77) | 0.016 | 4.38 (2.03-9.46) | <0.001 |
| Adjuvant chemotherapy | 1.24 (0.88-1.78) | 0.218 | 1.36 (0.90-2.05) | 0.144 |