Table 2.

Each indicator value of cortisol responsiveness after the metyrapone single administration.

Indicators	All (n =15)	Cushing’s disease (n =7)	Adrenal Cushing’s syndrome (n =8)	p value
Fnadir, nmol/L	264.8 (219.4 – 347.6)	364.1 (255.1 – 593.0)	253.7 (208.2 – 268.9)	0.08
ΔF, nmol/L	295.2 (241.4 – 367.9)	383.4 (302.0 – 506.2)	267.5 (205.5 – 297.2)	0.03
F reduction ratio	0.52 (0.44 – 0.66)	0.44 (0.41 – 0.67)	0.52 (0.49 – 0.57)	0.48
AUCF suppression ratio	0.39 (0.28 – 0.44)	0.27 (0.27 – 0.49)	0.39 (0.35 – 0.41)	0.81
time to the nadir, hour	2.0 (2.0 – 3.0)	2.0 (2.0 – 3.5)	2.5 (2.0 – 3.0)	0.75

Data were presented as median (IQR).

IQR, interquartile range.