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. 2024 Dec 23;15:1486861. doi: 10.3389/fendo.2024.1486861

Table 1.

Characteristics of studies.

Author Region Study design Sample size T2DM GDM criteria T2DM criteria Risk factors
JONATHAN R. STEINHART-1997 America Retrospective 111 47 NA WHO FBG; spontaneous abortions; GTT total; recurrent GDM; insulin use
Siri L-1998 America Retrospective 904 169 NDDG NDDG Contraception
NAM H. CHO1-2005 Korea Prospective 170 18 NDDG WHO Age; Gestational age at diagnosis of GDM; Pre-pregnancy BMI; Positive family history of diabetes; Higher FBG; Higher homocysteine level
N. Wah Cheung-2005 Australia Retrospective 102 30 NA NA BMI; FBG; OGTT 2-h; Insulin use in pregnancy
NAM H. CHO2-2005 Korea Prospective 909 116 NDDG NDDG Suprailiac skin fold thickness; tricep skin fold thickness; waist/hip ratio; BMI; subscapular skin fold thickness; weight; waist
Anny H Xiang-2006 America Prospective 526 106 NA ADA Depo-medroxyprogesterone acetate
Kristian Lo¨bner-2006 Germany Prospective 302 130 German Diabetes Association ADA Autoantibody positive; Insulin in pregnancy; BMI; Previous pregnancies
Anna J Lee-2007 Australia Retrospective 5,470 405 ADPSG WHO, 1998 Race; height; age; parity; BMI; birth weight; BwtGC; gestational age; insulin use in pregnancy; family history of diabetes; FBG; 1-h blood glucose; 2-h blood glucose
C Russell-2007 Canada Retrospective 1,401 251 Canadian Diabetes Association NA Weight; insulin use; neonatal hypoglycemia; subsequent pregnancies GDM
Anny H. Xiang-2010 Spain Prospective 72 31 NA ADA Intravenous glucose tolerance tests; basal glucose clearance; OGTT total area; OGTT-30 insulin; weight change; additional pregnancy; progestin-only method
Christian S. Go¨bl-2011 Austria Prospective 110 23 IADPSG WHO OGTT; Age; HDL-C; Insulin during pregnancy; RRS/RRD; TG; BMI; WC; FPG
A. H. Xiang-2011 America Retrospective 12,998 1539 IADPSG ADA Race
Tobias DK-2012 America Prospective 4,413 491 NA NDDG Healthful dietary patterns
Yujie Wang-2012 America Prospective 1,142 327 ADA WHO Age; BMI; race
Denice S. Feig-2013 Canada Retrospective 3,576 1292 NA NA Preeclampsia; gestational hypertension
Bao W-2014 America Prospective 4,554 635 NA NDDG Physical activity and sedentary behaviors
Huikun Liu-2014 China Retrospective 1,263 83 WHO ADA BMI
R.Retnakaran-2015 Canada Retrospective 23,363 5483 NA NA Pathophysiology; sex of the baby
Claire E Eades-2015 Scotland Prospective 164 41 an FBG of over 5.5 mmol/l-1 or blood glucose reading two hours (2 h BG) after an OGTT of over 9 mmol/l-1 WHO Weight gain during pregnancy; use of insulin during pregnancy; HbA1c levels at diagnosis of GDM; FBG
Valizadeh M-2015 Iran Retrospective 110 36 NA NA Parity; delivery and follow-up lab test interval; FBG; maternal weight; BMI; waist circumference; neonatal birth weight; age; family history of diabetes mellitus; history of delivering macrosomic neonate; insulin use
Joon Ho Moon-2015 Korea Prospective 418 53 NDDG ADA Postpartum BMI change
Pei-Chao LIN-2015 China Retrospective 71 29 NDDG ADA BMI; Insulin use during pregnancy
Piotr Molęda-2016 Poland Retrospective 199 13 OGTTs WHO Uric acid
Catherine R Chamberlain-2016 Australia Retrospective 289 82 ADPSG WHO BMI; breastfeeding;
Bao W1-2016 America Prospective 3,976 641 NA ADA Habitual iron intake
Bao W2-2016 America Prospective 1,695 259 NA ADA BMI; weight change
Bao W3-2016 America Prospective 4,502 722 NA ADA Low-carbohydrate diets scores
Deirdre K-2018 America Retrospective 347 172 NA NA Dietary Intakes; circulating concentrations of
branched-chain amino acids
Casagrande SS-2018 America Prospective 568 112 NA NA Age; years since GDM diagnosis; family history of diabetes; BMI; education
Yukari Kugishima-2018 Japan Retrospective 306 32 IADPSG WHO BMI; 2-h PG; HbA1c; Insulin therapy during pregnancy
Judith Bernstein-2019 Boston Retrospective 1,091 58 NA NA GDM recurrence; delivery interval
Tawanda Chivese-2019 South Africa Retrospective 150 47 IADPSG WHO, 2006 Waist circumference; Hip circumference; BMI; age at follow-up; secondary and matric education; dyslipidemia; hypertension; family history of diabetes; total physical activity
Ley SH-2020 America Retrospective 4,372 873 NA NDDG Lactation duration
Kawasaki M-2020 East Asia Retrospective 399 43 Japan Society of Obstetrics and Gynecology criteria; IADPSG criteria WHO BMI; ppOGTT 2-h plasma glucose; ppOGTT HbA1c ≥5.7% age at childbirth; family history of diabetes; GDM diagnosis before 20 weeks gestation; use of insulin during pregnancy; macrosomia
Dayeon Shin-2021 Korea Prospective 629 NA NA T2DM refers to a woman diagnosed with diabetes by a doctor or an FBG level ≥126 mg/dL. Pre-pregnancy BMI
Pandora L. Wander-2021 America Prospective 335 / NA ADA Adiposity and related biomarkers; sex hormone-binding globulin; alanine aminotransferase
Stefanie N Hinkle-2021 America Retrospective 4,740 897 NA NDDG Habitual alcohol consumption
Chiou YL-2021 China Prospective 57 24 NA HbA1c ≥ 6.5% Education level; pre-pregnancy BMI; 100-g OGTT FBG; 100-g OGTT 1-h blood glucose; 75-g OGTT FBG; 75-g OGTT 2-h blood glucose
Anna J Wood-2021 Australia Prospective 82 11 IADPSG; WHO WHO Demographics; age; multiparity; family history of diabetes; increased glucose values; insulin use; BMI
Enav Yefet-2022 Israel Retrospective 788 178 NA NDDG Recurrent GDM; maternal and obstetrical characteristics of the GDM pregnancy; the consecutive pregnancy including BMI gain and inter-pregnancy interval
Jiaxi Yang-2022 America Prospective 4,522 979 NDDG ADA Habitual coffee consumption
Mi Jin Choi-2022 Korea Retrospective 5,781 302 ADA WHO BMI; FBG; age; family history of diabetes; hypertension; insulin use during pregnancy
Roosa P-2022 Finland Prospective 96,353 5370 IADPSG NA Insulin therapy during GDM
Yumei Wei-2022 China Retrospective 1,002 23 IADPSG ADA Pre-pregnancy BMI; age; IFG; history of macrosomia; weight change between twice pregnancy; gestational interval
Amir Naeh Israel Retrospective 1,812 119 NDDG WHO Multifetal pregnancy
Deirdre K Tobias-2024 America Prospective 350 175 NA ADA Metabolomics score; amino acid and lipid sub‐scores

GTT, Glucose Tolerance Test; GDM, Gestational Diabetes Mellitus; BMI, Body Mass Index; FBG, Fasting Blood Glucose; OGTT, Oral Glucose Tolerance Test; BwtGC, Birth Weight Gestational Centile; HDL-C, High-Density Lipoprotein Cholesterol; RRS/RRD, Systolic and Diastolic Blood Pressure; TG, Triglycerides; WC, Waist Circumference; FPG, Fasting Plasma Glucose; PG, Plasma Glucose; PP, Postpartum; PM, Particulate Matter.

NA, Not Applicable.