Table 2.
Clinical characteristics according to serum uric acid levels in women
| Variables | Uric acid categories, mg/dL | p value | |||
|---|---|---|---|---|---|
| ≤4.0 | 4.0 to ≤5.0 | 5.0 to ≤6.0 | 6.0< | ||
| (n = 91) | (n = 221) | (n = 166) | (n = 120) | ||
| Uric acid, mg/dL | 3.32 ± 0.51 | 4.48 ± 0.27 | 5.46 ± 0.29 | 6.87 ± 0.87 | NA |
| Age, y | 62.4 ± 13.2 | 66.0 ± 11.5 | 67.2 ± 10.6 | 68.0 ± 13.3 | 0.004 |
| Body mass index, kg/m2 | 21.3 ± 3.0 | 23.0 ± 3.9 | 24.3 ± 4.2 | 24.1 ± 4.3 | <0.001 |
| Systolic blood pressure, mm Hg | 129.8 ± 18.3 | 131.4 ± 18.5 | 132.9 ± 19.6 | 132.5 ± 18.8 | 0.59 |
| Diastolic blood pressure, mm Hg | 75.6 ± 11.7 | 75.8 ± 12.0 | 77.6 ± 12.3 | 74.4 ± 11.4 | 0.15 |
| Heart rate, bpm | 69.8 ± 9.1 | 71.4 ± 11.8 | 69.1 ± 10.6 | 70.7 ± 12.5 | 0.20 |
| Total cholesterol, mg/dL | 204.6 ± 42.3 | 199.5 ± 37.8 | 203.5 ± 35.4 | 197.6 ± 32.6 | 0.40 |
| Triglycerides, mg/dL | 111.6 ± 63.9 | 117.7 ± 71.3 | 134.5 ± 76.1 | 136.6 ± 78.9 | 0.01 |
| HDL-cholesterol, mg/dL | 68.3 ± 19.5 | 65.2 ± 16.7 | 61.1 ± 15.5 | 61.4 ± 16.2 | 0.002 |
| LDL-cholesterol, mg/dL | 120.3 ± 37.6 | 113.8 ± 34.0 | 120.2 ± 31.0 | 111.4 ± 31.2 | 0.07 |
| Glucose, mmol/L | 109.8 ± 28.1 | 112.2 ± 35.1 | 112.1 ± 41.4 | 117.2 ± 41.8 | 0.53 |
| eGFR, mL/min/1.73 m2 | 79.9 ± 14.0 | 72.0 ± 17.9 | 67.6 ± 16.4 | 63.6 ± 51.0 | <0.001 |
| Hypertension, n (%) | 58 (64.4) | 182 (82.4) | 153 (92.2) | 105 (87.5) | <0.001 |
| Dyslipidemia, n (%) | 62 (68.9) | 171 (77.4) | 142 (85.5) | 100 (83.3) | 0.001 |
| Diabetes mellitus, n (%) | 23 (25.6) | 79 (35.9) | 49 (29.5) | 41 (34.5) | 0.25 |
| Coronary artery disease, n (%) | 3 (3.3) | 13 (5.9) | 5 (3.0) | 9 (7.6) | 0.26 |
| Cerebrovascular disease, n (%) | 5 (5.6) | 14 (6.4) | 10 (6.0) | 7 (5.9) | 0.99 |
| Smoking, n (%) | 16 (18.0) | 39 (17.7) | 34 (20.6) | 27 (22.5) | 0.71 |
| Chronic kidney disease, n (%) | 4 (4.4) | 46 (20.9) | 58 (34.9) | 68 (57.1) | <0.001 |
| Diuretics, n (%) | 1 (1.1) | 20 (9.1) | 33 (20.0) | 21 (17.7) | <0.001 |
HDL indicates high-density lipoprotein, LDL low-density lipoprotein, eGFR estimated glomerular filtration rate, NA not applicable
p values for comparisons across the uric acid categories were performed with ANOVA for continuous variables and χ2 test for categorical variables