Table 3.
Multivariate analysis of the relation between vascular smooth muscle dysfunction and variables in women
| Variables | Model 1 | Model 2 | Model 3 | Model 4 | Model 5 | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| OR (95%CI) | p value | OR (95%CI) | p value | OR (95%CI) | p value | OR (95%CI) | p value | OR (95%CI) | p value | |
| Uric acid (mg/dL) | 1.31 (1.14–1.51) | <0.001 | 1.20 (1.04–1.40) | 0.01 | 1.17 (0.98–1.39) | 0.08 | 1.28 (1.02–1.43) | 0.03 | 1.21 (1.02–1.43) | 0.03 |
| Age (years) | — | — | 1.07 (1.05–1.09) | <0.001 | 1.06 (1.04–1.09) | <0.001 | 1.07 (1.04–1.09) | <0.001 | 1.07 (1.04–1.09) | <0.001 |
| Body mass index (kg/m2) | — | — | — | — | 1.00 (0.95–1.05) | 0.92 | — | — | 1.00 (0.95–1.05) | 0.92 |
| Body mass index ≥25 (kg/m2) | — | — | — | — | — | — | 0.98 (0.63–1.51) | 0.98 | — | — |
| Hypertension (yes/no) | — | — | — | — | 2.49 (1.30–4.79) | 0.006 | 2.55 (1.33–4.90) | 0.005 | 2.52 (1.31–4.86) | 0.006 |
| Dyslipidemia (yes/no) | — | — | — | — | 0.90 (0.54–1.50) | 0.68 | 0.90 (0.54–1.50) | 0.68 | 0.89 (0.53–1.49) | 0.66 |
| Diabetes mellitus (yes/no) | — | — | — | — | 1.90 (1.26–2.87) | 0.002 | 1.90 (1.26–2.86) | 0.002 | 1.89 (1.25–2.85) | 0.002 |
| Smoking (yes/no) | — | — | — | — | 0.85 (0.51–1.44) | 0.56 | 0.85 (0.51–1.44) | 0.55 | 0.85 (0.51–1.44) | 0.55 |
| eGFR (ml/min/1.73m2) | — | — | — | — | — | — | 1.00 (0.99–1.01) | 0.83 | 1.00 (0.99–1.01) | 0.83 |
| Chronic kidney disease (yes/no) | — | — | — | — | 1.19 (0.76–1.86) | 0.46 | — | — | — | — |
| Coronary artery disease (yes/no) | — | — | — | — | 0.81 (0.34–1.95) | 0.64 | 0.84 (0.35–2.04) | 0.70 | 0.84 (0.35–2.03) | 0.70 |
| Cerebrovascular disease (yes/no) | — | — | — | — | 4.21 (1.92–9.24) | <0.001 | 4.16 (1.89–9.17) | <0.001 | 4.18 (1.90–9.19) | <0.001 |
| Diuretics (yes/no) | — | — | — | — | 1.16 (0.67–2.01) | 0.61 | 1.17 (0.67–2.04) | 0.58 | 1.17 (0.67–2.03) | 0.59 |
OR odds ratio, CI confidence interval, eGFR estimated glomerular filtration rate