Table 3.

Multivariable analyses for predicting a complicated inflammatory bowel disease (IBD) course using fecal biomarkers. Model 1 = using fecal calprotectin. Model 2 = using fecal myeloperoxidase.

All IBD Patients (N = 171)	Multivariable Analysis (Model 1)		Multivariable Analysis (Model 2)
Variable	Odds Ratio (95% CI)	P	Odds Ratio (95% CI)	P
Current steroids	0.39 (0.10-1.61)	0.19	0.57 (0.16-2.11)	.40
Steroids in last year	5.88 (2.05-16.88)	<0.001	5.35 (1.94-14.78)	.001
Biological agent use	1.43 (0.56-3.64)	0.46	1.88 (0.75-4.67)	.18
Albumin	0.87 (0.76-0.98)	0.02	0.89 (0.79-1.00)	.05
fCal ≥ 250 ug/g	7.85 (3.38-18.26)	<0.001
fMPO ≥ 12 ug/g			4.43 (2.03-9.64)	<.001
Subjectively active IBD at baseline (HBI > 4, SCCAI > 5)	2.95 (1.27-6.88)	0.01	2.83 (1.25-6.43)	.01

Abbreviations: UC, ulcerative colitis; CD, Crohn’s disease; HBI, Harvey-Bradshaw index for CD; SCCAI, Simple clinical colitis activity index for UC.