Table 3.

Logistic regression models to assess contributing factors to subsequent phenotypes.

Subsequent phenotype	n	Variables	Odds ratio (95% CI)	P value
Diffuse inflammation of the pouch body	65	Disease extent E3	3.79 (1.09-13.2)	.036 a
		Age at diagnosis ≥18 y	0.47 (0.23-0.95)	.036 a
		Primary AL involvement	2.69 (1.36-5.31)	.004 a
Pouch-related fistulas	32	Primary AL involvement	2.35 (0.99-5.58)	.053
		Primary diffuse inflammation	1.99 (0.87-4.56)	.10
		Primary focal inflammation	0.34 (0.15-0.78)	.011 a
AL/IL stenosesb	40	Age at colectomy ≥18 y	0.24 (0.09-0.63)	.0037 a
		Preoperative anti-TNF-α drugs	0.41 (0.18-0.91)	.029 a
		Primary pouch-related fistulas	2.09 (0.97-4.49)	.06
		Primary normal pouch	0.19 (0.04-0.84)	.028 a
Normal pouch	62	Primary AL involvement	0.72 (0.32-1.63)	.43
		Primary IL involvement	0.68 (0.31-1.50)	.34
		Primary diffuse inflammation	0.57 (0.26-1.22)	.15
		Primary pouch-related fistulas	0.17 (0.06-0.48)	<.001 a

Abbreviations: AL, afferent limb; CI, confidence interval; IL, inlet; TNF, tumor necrosis factor.

^aValues indicate statistical significance (P < .05).

^bFour factors showing P < .01 (Table S6) were preferentially selected to avoid overfitting.