Table 3.

Fertility outcomes, pregnancy complications, and adult cardiovascular disease and diabetes type II according to menstrual cycle pattern in adolescence (15 years) and at age 38–40 years.

	Adolescent menstrual cycle pattern
	Regular		Oligomenorrhea
	Adult menstrual cycle pattern
	Regular	Oligomenorrhea	Regular	Oligomenorrhea
Ado-adult subgroup	REGREG	REGOL	OLREG	OLOL
	Fertility outcome				P-value
	n=81	n=15	n=26	n=21
Subfertility >12 months	11 (14%)	6 (40.0%)	5 (19%)	7 (33%)	0.04
Fertility treatment (FT)	11 (14%)	3 (20%)	5 (19%)	9 (43%)	0.03
Ovulation disorder main reason for FT	3 (4%)	0 (0%)	2 (4%)	7 (33%)	0.001
Ovulation disorder mentioned.
as main or secondary reason for FT	3 (4%)	2 (13%)	2(4%)	7(33%)	0.003
Time to pregnancy—months mean (SD)*	6.5 (9.6)	17.4 (22.1)	12.6 (19.6)	13.9 (18.4)	0.05
	Pregnancy complications
	n=74	n=15	n=24	n=21
Pregnancy induced hypertension including pre-eclampia	13 (18%)	3 (20%)	4 (15%)	4 (19%)	0.98
Gestational diabetes	0	0	0	3 (15%)	0.001
Caesarean section	16 (22%)	3 (20%)	3 (12%)	4 (19%)	0.77
	Cardiovascular disease and type 2 diabetes
	n=93	n=15	n=31	n=21
Diabetes type II	1 (1%)	0	0	1 (5%)	0.44
High Cholesterol	3 (3%)	0	0	1 (5%)	0.62
Hypertension	3 (3%)	1 (6%)	2 (7%)	2 (9%)	0.62
Coronary or vascular disease	1 (1%)	0	0	0	0.89
Combined	6 (7%)	1 (6%)	2 (7%)	3(14%)	0.66

^*Those with infertility (no conception) excluded.

Data are presented as mean (SD) or number in subgroup (% in subgroup).

P-value for means: one-way ANOVA; P-value for proportions chi-square for multiple groups. Non-parametric Kruskal–Wallis test. Significant outcomes (P < 0.05) are presented in bold.