Table 2.
Laboratory and clinical characteristics of ICU and IDU patients.
| Laboratory parameters | IDU patients (n = 18) | ICU patients (n = 17) | p-value |
|---|---|---|---|
| Lymphocyte count (cells/mm3) | 0.8 ± 0.17 | 0.66 ± 0.21 | <0.01 |
| LDH (U/L) | 431 ± 232 | 926 ± 476 | <0.001 |
| D-dimer (ng/ml) | 1,027 (228, 24,582) | 1,597 (681, 329,800) | NS |
| Ferritin (ng/ml) | 1,035 (42, 6,155) | 1,117 (32, 9,667) | NS |
| CRP (mg/dl) | 9.6 ± 6.7 | 12.8 ± 7.7 | NS |
| IL-6 (pg/ml) | 62 (7, 143) | 61 (31, 924) | NS |
| Clinical parameters | |||
| Days of hospitalization | 8 ± 5 | 15 ± 12 | <0.05 |
| Mortality (n, %) | 0 | 11 (64.7%) | |
| SOFA | 2 (0.4) | 3 (0, 9) | <0.05 |
| SAPS | – | 33 (13, 71) | |
| CT score | 11 ± 4.8 | 15 ± 6.8 | <0.05 |
| PaO2/FiO2 on admission | 194 (32, 410) | 67 (43, 388) | <0.05 |
| Mechanical ventilation (days) | – | 4 (0, 19) | |
| Kidney replacement therapy (n, %) | – | 3 (17%) | |
| Vasopressor therapy (n, %) | – | 13 (76%) | |
Data are presented as mean ± standard deviation or median (minimum, maximum). Differences were considered significant when the P value was equal to or less than 0.05. ICU, Intensive care unit; IDU, infectious disease unit; HC, healthy control; LDH, lactate dehydrogenase; CRP, C-reactive protein; IL-6, interleukin-6; SOFA, Sequential organ failure assessment score; SAPS, simplified acute physiology score; CT score, computed tomography score; NS, not significant. Significant results are presented in bold.