TABLE 1.
Demographic, baseline clinical characteristics of SA-AKI patients.
Variables | All patients (n = 48) | Survivors (n = 22) | Non-survivors (n = 26) | t/χ 2 /Z | P-value |
---|---|---|---|---|---|
Age (y) a | 61.5 (50.5.67.8) | 62.500 (35.8.70.0) | 60.500 (54.5.65.5) | −0.031 | 0.975 |
Male sex, n (%) d | 37 (77.08) | 16 (72.73) | 21 (80.77) | 0.436 | 0.509 |
WBC (×109/L) a | 11.808 (6.90.19.87) | 9.689 (6.2.26.8) | 12.423 (8.9.18.4) | −0.538 | 0.591 |
NEUT%, (%) c | 89.818 ± 7.683 | 91.96 ± 8.41 | 88.00 ± 6.64 | 1.823 | 0.075 |
HGB, (g/L) a | 96.28 (81.13,118.19) | 102.080 (81.6,120.9) | 89.725 (80.3,116.4) | −0.859 | 0.39 |
PLT (×109/L) a | 102.46 (50.83,142.42) | 121.955 (57.9,140.0) | 57.855 (50.3,168.8) | −0.393 | 0.694 |
sCr (μmol/L) a | 213.596 (172.90,354.67) | 329.086 (171.4,359.3) | 206.208 (173.6,271.4) | −0.869 | 0.385 |
BUN (mmol/) c | 22.724 (15.36.27.74) | 19.372 (14.9.24.8) | 26.725 (19.6.34.2) | −2.359 | 0.018* |
CO2 (mmol/L) a | 21.385 (18.92.22.9) | 21.295 (18.3.22.5) | 21.400 (18.1.23.0) | −0.331 | 0.741 |
ALB (g/L) a | 29.38 ± 3.883 | 29.84 ± 3.91 | 28.99 ± 3.89 | 0.744 | 0.461 |
AST (U/L) a | 86.1 (55.08,234.82) | 73.185 (43.7,246.8) | 93.060 (77.2,167.4) | −0.879 | 0.379 |
ALT (U/L) a | 49.72 (33.66,205.64) | 59.180 (27.6,219.1) | 48.880 (45.4.89.4) | −0.186 | 0.852 |
TBIL (μmol/L) a | 28.38 (14.21,255.03) | 26.495 (11.4.34.5) | 244.199 (14.7,478.1) | −3.021 | 0.003** |
DBIL (μmol/L) a | 21.474 (7.45,213.74) | 12.907 (8.1.31.2) | 204.665 (7.2,440.6) | −2.193 | 0.028* |
IBIL (μmol/L) a | 9.695 (7.00.36.00) | 8.623 (3.0.12.2) | 35.287 (7.5.40.2) | −3.414 | 0.001** |
PCT (ng/mL) a | 23.545 (6.95.40.19) | 24.544 (12.0.45.1) | 22.903 (6.2.39.4) | −1.076 | 0.282 |
SA-AKI stage III, n (%) b | 45 (93.75) | 19 (86.36) | 26 (100.00) | 3.782 | 0.052 |
APACHE II a | 20.729 ± 8.22 | 19.82 ± 10.71 | 21.50 ± 5.42 | −0.668 | 0.509 |
SOFA a | 10 (8.00.16.25) | 8.500 (7.0.11.3) | 12.000 (9.8.18.0) | −3.104 | 0.002** |
Mechanical ventilation, n (%) d | 17 (35.42) | 2 (9.09) | 15 (57.69) | 12.306 | 0.000** |
Need of vasopressor, n (%) d | 20 (41.67) | 5 (22.73) | 15 (57.69) | 5.994 | 0.014* |
Oliguria, n (%) d | 19 (39.58) | 9 (40.91) | 10 (38.46) | 0.03 | 0.863 |
Abbreviations: WBC, white blood cell; NEUT%, neutrophil%; HGB, haemoglobin; PLT, platelet; sCr, serum creatinine; BUN, urea nitrogen; ALB, albumin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALT, glutamic-pyruvic transaminase; TBIL, total bilirubin; DBIL, Direct bilirubin; IBIL, Indirect bilirubin; PCT, procalcitonin; APACHE II Score, Acute Physiology and Chronic Health Evaluation II, Score; SOFA, Score, Sequential Organ Failure Assessment.
Values are expressed as median (interquartile range) (Mann–Whitney U-test).
Values are expressed as number (percentage) (Fisher’s exact test).
Values are expressed as mean ± standard deviation (Student’s t-test).
Values are expressed as number (percentage) (continuous correction chi-square test).
*P < 0.05, **P < 0.01.