Table 2.
Dose constraints and results from the optimized treatment plans for cases 1 and 2
| Structure | Dose constraints | Case 1 | Case 2 |
|---|---|---|---|
| Target volume | |||
| PTV | V100% ≥95 (%) | 94.57 | 73.52 |
| Dmax (Gy) | 49.69 | 49.43 | |
| CI | 0.79 | 0.72 | |
| GI | 4.36 | 4.07 | |
| GIlow | 13.24 | 15.87 | |
| GIhigh | 1.93 | 1.83 | |
| OARs (excluding cardiac adjacent structures) | |||
| Spinal cord | Dmax ≤14 (Gy) | 2.98 | 6.73 |
| D1.2mL ≤8 (Gy) | 2.51 | 5.49 | |
| Esophagus | D5mL ≤15.4 (Gy) | 0.25 | 9.86 |
| Stomach | D5mL ≤22 (Gy) | - | 16.59 |
| Lung total | RV7Gy ≤1,500 (mL) | 70.54 | 423.22 |
| Liver | RV11Gy ≤700 (mL) | - | 3.49 |
| OARs (Including heart-related structures) | |||
| Heart (excluding PTV) | D50% (Gy) | 1.31 | 7.23 |
| Aorta | Dmax ≤20.0 (Gy) | 5.06 | 19.82 |
| Left coronary artery | Dmax ≤14.0 (Gy) | 14.05 | 31.54 |
| Left atrium | Dmax ≤4.4 (Gy) | 12.05 | -a) |
PTV, planning target volume; V100%, percent volume receiving 100% of the prescribed dose at the structure; CI, conformity index; GI, gradient index; GIlow, GI for low dose; GIhigh, GI for high dose; OAR, organ-at-risk; RV, reverse volume; Dmax, maximum dose irradiated to the structure; D1.2mL/D5mL, dose irradiated to 1.2ml/5ml of the structure; RV7Gy/RV11Gy, normal tissue volume receiving < 7 Gy/11 Gy; D50%, dose irradiated to 50% of volume of the structure.
a)
Target overlapped with the left atrium.