Figure 6.

Overview of Census framework. Census is built upon the TileDB-SOMA framework to enable computational scientists to execute complex and specific queries across over 65 million cell measurements compiled from 900+ datasets spanning human and mouse organs available in CZ CELLxGENE using Census. Leveraging out-of-core processing, SOMA provides the API and data model to facilitate the storage, retrieval and analysis of datasets exceeding memory capacity. The standardized schema required by the data portal enables users to effortlessly query and export any segment of the extensive 65+ million cell dataset for in-depth analysis using Python and R.