Table 3.
Clinical characteristics and detailed information of the blood culture results of patients who had positive or negative ddPCR results
| All patients (n = 81) | Patients with positive ddPCR results (n = 67) | Patients with negative ddPCR results (n = 14) | P value | |
|---|---|---|---|---|
| Age (years), median (IQR) | 74 (66–82) | 75 (60–82) | 70 (56–79) | 0.14 |
| Male, n (%) | 46 (56.8) | 38 (56.7) | 8 (57.1) | 0.97 |
| Primary site of BSI | ||||
| Abdominal infection, n (%) | 42 (51.9) | 38 (56.7) | 4 (28.6) | 0.078 |
| Bile duct infection, n (%) | 34 (42.0) | 30 (44.8) | 4 (28.6) | 0.37 |
| Intestinal perforation, n (%) | 5 (6.2) | 5 (7.5) | 0 (0) | 0.58 |
| Urinary tract infection, n (%) | 33(40.1) | 24 (35.8) | 8 (57.1) | 0.14 |
| Others, n (%) | 6 (7.4) | 5 (7.5) | 2 (14.3) | 0.60 |
| BSI caused by ESBL-producing E. coli, n (%) | 19 (23.5) | 15 (22.4) | 4 (28.6) | 0.73 |
| Septic shock, n (%) | 17 (21.0) | 17 (25.4) | 0(0) | 0.034 |
| 28-day mortality, n (%) | 8 (9.9) | 8 (11.9) | 0(0) | 0.34 |
| Blood culture | ||||
| TTP (h), median (IQR) | 9.1 (8.4–10.5) | 8.8 (8.3–10.1) | 10.7 (9.9–12.5) | < 0.001 |
| Positive for two sets of blood culture, n (%) | 65 (80.2) | 60 (89.6) | 5 (35.1) | < 0.001 |
| No. of positive bottle of two sets of blood culture | ||||
| 4 bottles, n (%) | 50 (61.7) | 48 (71.6) | 2 (14.3) | < 0.001 |
| 3 bottles, n (%) | 10 (12.5) | 7 (10.5) | 3 (21.4) | 0.37 |
| 2 bottles, n (%) | 10 (12.5) | 10 (14.3) | 0 (0) | 0.20 |
| 2 bottles of different sets, n (%) | 5 (6.3) | 5 (7.5) | 0 (0) | 0.58 |
| 1 bottle, n (%) | 11 (13.8) | 2 (3.0) | 9 (64.3) | < 0.001 |
ESBL, extended-spectrum β-lactamase IQR, interquartile range; TTP, Time-to-positivity; ESBL, Extended-Spectrum β-Lactamase