Fig. 9.

Post-hoc analysis after stratification of glaucomatous donors. Progressive RGC degeneration and increased glial reactivity were observed in the retina with disease severity. A Loss of RBPMS + RGC cells, B loss of axons (NEFL), C increased astrocytic activation (GFAP), and D microglia/macrophage activation (IBA1) was stratified by disease state. Horizontal bars indicate mean ± standard deviation. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, One-way Analysis of variance (ANOVA) followed by Tukey’s multiple comparison test