TABLE 1.

Comparison of two trials.

	The OCTOBER study	The ILUMIEN IV study
Population	Patients with bifurcation lesions	Patients with high clinical and/or high coronary artery lesion risk
Average age	65.6 years	66.3 years
Diabetes	16.7%	42.0%
Bifurcation lesions	100%	3.3%
Long or multiple lesions*	Unknown	67.4%
Intervention	OCT‐guided PCI	OCT‐guided PCI
Comparison	Angiography‐guided PCI	Angiography‐guided PCI
Primary end point	MACE**	MSA and TVF***
Median follow‐up	2 years	2 years
Study design	Multicenter RCT	Multicenter RCT

Abbreviations: MACE, major adverse cardiac events; MSA, minimum stent area; OCT, optical coherence tomography; PCI, percutaneous coronary intervention; RCT, randomized controlled trials; TVF, target vessel failure.

^*Expected stent length longer than 28 mm.

^**A composite of cardiac cause, target‐lesion myocardial infarction, or ischemia‐driven target‐lesion revascularization.

^***A composite of death from cardiac causes, target‐vessel myocardial infarction, or ischemia‐driven target‐vessel revascularization.