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IC50 values of PRIMA‐1met and oxaliplatin in different CRC cell lines.
| Cell line | p53 status | IC50 | |
|---|---|---|---|
| PRIMA‐1met (μM) | Oxaliplatin (μM) | ||
| HCT116 | Wild‐type | 31 | 0.029 |
| RKO | Wild‐type | 46 | 24 |
| HCT15 | Mutant, P153A | 76 | 130 |
| SW620 | Mutant, R237H | 50 | 52 |
| DLD‐1 | Mutant, S241F | 33 | 93 |
