TABLE 1.
Weighted Features of the Study Population Based on Controlled Attenuation Parameters (CAP)
| Study population | Non-MASLD (CAP <263, n=2835) | MASLD (CAP ≥263, n=3098) | P |
|---|---|---|---|
| Age (y) | 46.3±17.9 | 49.8±16.6 | <0.0001 |
| Gender (%) | <0.0001 | ||
| Man | 40.5 | 50.9 | |
| Woman | 59.5 | 49.1 | |
| Race/ethnicity (%) | <0.0001 | ||
| Mexican American | 6.7 | 11.3 | |
| Other Hispanic | 8.0 | 7.5 | |
| Non-Hispanic White | 61.3 | 61.8 | |
| Non-Hispanic Black | 13.7 | 9.2 | |
| Other races | 10.4 | 10.3 | |
| Education level (%) | 0.0006 | ||
| Less than high school | 9.4 | 10.9 | |
| High school | 23.7 | 27.0 | |
| More than high school | 66.9 | 62.1 | |
| Smoked at least 100 cigarettes | 0.0020 | ||
| Yes | 34.5 | 38.3 | |
| No | 65.5 | 61.7 | |
| Total PA (MET hours/week) | 79.2±119.3 | 70.0±110.4 | 0.0019 |
| Leisure-time PA (MET hours/week) | 19.1±30.8 | 13.0±23.7 | <0.0001 |
| Occupation-related PA (MET hours/week) | 56.7±110.6 | 53.4±102.0 | 0.2277 |
| Transportation-related PA (MET hours/week) | 3.4±12.8 | 3.6±16.4 | 0.7485 |
| LSM (kPa) | 4.8±2.8 | 6.4±5.4 | <0.0001 |
| BMI (kg/m2) | 27.1±5.2 | 33.3±7.0 | <0.0001 |
| WHR | 0.9±0.1 | 1.0±0.1 | <0.0001 |
| Laboratory features | |||
| ALT (IU/L) | 19.1±12.3 | 26.4±17.9 | <0.0001 |
| AST (IU/L) | 20.2±8.6 | 22.6±12.3 | <0.0001 |
| ALP (IU/L) | 73.0±23.3 | 78.5±22.7 | <0.0001 |
| GGT (IU/L) | 22.7±26.3 | 33.1±37.0 | <0.0001 |
| Total cholesterol (mmol/L) | 4.8±1.0 | 4.9±1.0 | 0.0017 |
| Triglyceride (mmol/L) | 1.3±0.8 | 1.9±1.3 | <0.0001 |
| HDL-cholesterol (mmol/L) | 1.5±0.4 | 1.3±0.4 | <0.0001 |
| UA (µmol/L) | 296.6±78.4 | 337.0±84.9 | <0.0001 |
| CRP (mg/L) | 3.1±6.9 | 4.4±6.7 | <0.0001 |
| Glycohemoglobin (%) | 5.5±0.7 | 5.9±1.1 | <0.0001 |
Mean±SD for continuous variables: P-value was calculated by weighted linear regression model.
% for categorical variables: P-value was calculated by weighted χ2 test.
ALP indicates alkaline phosphatase; ALT, alanine transaminase; AST, aspartate aminotransferase; BMI, body mass index; CAP, controlled attenuation parameter; CRP, C-reactive protein; GGT, gamma glutamyl transferase; HDL-cholesterol, high-density lipoprotein cholesterol; LSM, liver stiffness measure; MET, metabolic equivalent; UA, uric acid; WHR, waist-to-hip ratio.