Table 2.
Echocardiographic data of the studied patients.
| All patients N = 71 |
Groups | P value | |||
|---|---|---|---|---|---|
|
| |||||
| Idiopathic and heritable pulmonary hypertension (group 1.1 and 1.2) N = 39 |
PH secondary to CHD (group 1.4.4) N = 27 |
PH secondary to miscellaneous causes (group 5) N = 5 |
|||
| TR PG | |||||
| Minimum–maximum | 40.00–160.00 | 40.00–160.00 | 45.00–115.00 | 55.00–154.00 | 0.23 |
| Mean – SD | 84.02 ± 28.71 | 85.71 ± 30.70 | 76.39 ± 19.11 | 99.80 ± 39.50 | |
| Median | 78.00 | 82.00 | 70.00 | 100.00 | |
| IQR | 60.25 to 102.50 | 59.25 to 103.75 | 63.35 to 90.25 | 66.25 to 128.50 | |
| PR PG | |||||
| Minimum–maximum | 2.60–70.00 | 17.00–70.00 | 2.60–60.00 | 19.00–61.00 | 0.91 |
| Mean – SD | 36.28 ± 12.89 | 35.91 ± 12.59 | 36.31 ± 12.98 | 38.60 ± 17.04 | |
| Median | 37.00 | 35.00 | 39.00 | 40.00 | |
| IQR | 25.50 to 44.75 | 25.00 to 43.75 | 27.75 to 44.25 | 23.50 to 51.25 | |
| MPA | |||||
| Minimum–maximum | 14.00–43.00 | 14.00–35.00 | 14.00–43.00 | 17.00–25.00 | 0.06 |
| Mean – SD | 24.22 ± 5.348 | 23.37 ± 4.56 | 26.21 ± 6.33 | 21.60 ± 2.97 | |
| Median | 24.00 | 24.00 | 25.50 | 22.00 | |
| IQR | 21.00 to 27.00 | 20.00 to 26.00 | 21.50 to 29.00 | 20.00 to 23.50 | |
| MPA z score | |||||
| Minimum–maximum | 0.00–5.40 | 0.00–4.39 | 0.20–5.40 | 0.66–4.30 | 0.19 |
| Mean – SD | 2.31 ± 1.28 | 2.11 ± 1.11 | 2.71 ± 1.48 | 2.03 ± 1.35 | |
| Median | 2.20 | 2.16 | 2.50 | 1.74 | |
| IQR | 1.41 to 3.12 | 1.22 to 2.81 | 1.85 to 3.91 | 1.44 to 2.40 | |
| RA area | |||||
| Minimum–maximum | 4.30–40.60 | 5.00–40.60 | 4.30–25.50 | 5.50–11.50 | 0.05 |
| Mean – SD | 13.35 ± 6.97 | 14.87 ± 7.82 | 11.79 ± 5.33 | 8.88 ± 2.19 | |
| Median | 11.65 | 12.90 | 11.30 | 9.00 | |
| IQR | 9.00 to 15.60 | 10.20 to 16.40 | 7.57 to 14.47 | 7.82 to 10.22 | |
| RA area z score | |||||
| Minimum–maximum | −1.00–10.30 | −0.90–10.30 | −1.00–5.00 | 0.00–4.90 | *0.02 |
| Mean – SD | 2.60 ± 2.13 | 3.24 ± 2.28 | 1.80 ± 1.52 | 1.57 ± 2.05 | |
| Median | 2.50 | 2.78 | 1.90 | 0.87 | |
| IQR | 0.97 to 3.59 | 1.83 to 4.54 | 0.42 to 2.95 | 0.00 to 2.80 | |
| RV/LV ratio | |||||
| Minimum–maximum | 0.40–2.40 | 0.40–2.40 | 0.42–1.42 | 0.78–1.40 | *0.001 |
| Mean – SD | 1.13 ± 0.50 | 1.30 ± 0.53 | 0.82 ± 0.30 | 1.08 ± 0.28 | |
| Median | 1.00 | 1.15 | 0.77 | 0.95 | |
| IQR | 0.77 to 1.40 | 0.90 to 1.75 | 0.63 to 0.97 | 0.89 to 1.37 | |
| RVEDD | |||||
| Minimum–maximum | 1.30–5.10 | 1.30–5.10 | 1.60–4.10 | 2.00–3.50 | 0.09 |
| Mean – SD | 3.00 ± 0.79 | 3.18 ± 0.83 | 2.74 ± 0.68 | 2.78 ± 0.68 | |
| Median | 3.00 | 3.20 | 2.60 | 2.80 | |
| IQR | 2.50 to 3.50 | 2.70 to 3.70 | 2.30 to 3.10 | 2.15 to 3.42 | |
| RVEDD z score | |||||
| Minimum–maximum | 1.80–18.60 | 1.80–18.60 | 2.90–12.80 | 5.00–10.00 | 0.07 |
| Mean – SD | 8.35 ± 3.31 | 9.14 ± 3.52 | 7.15 ± 2.80 | 7.63 ± 2.34 | |
| Median | 8.30 | 8.71 | 6.97 | 7.44 | |
| IQR | 5.92 to 10.50 | 7.00 to 11.70 | 5.00 to 9.10 | 5.52 to 10.00 | |
| RVOT acceleration time | |||||
| Minimum–maximum | 40.00–113.00 | 40.00–105.00 | 60.00–113.00 | 46.00–78.00 | 0.30 |
| Mean – SD | 71.33 ± 13.82 | 69.90 ± 14.16 | 74.78 ± 13.26 | 66.60 ± 12.759 | |
| Median | 72.00 | 70.00 | 72.00 | 72.00 | |
| IQR | 61.25 to 80.00 | 61.00 to 79.50 | 66.25 to 80.75 | 58.75 to 75.00 | |
| TAPSE | |||||
| Minimum–maximum | 9.00–28.00 | 9.00–25.00 | 9.00–28.00 | 11.00–19.00 | 0.17 |
| Mean – SD | 16.12 ± 4.73 | 15.49 ± 4.51 | 17.56 ± 5.151 | 14.40 ± 3.21 | |
| Median | 16.00 | 15.00 | 17.00 | 14.00 | |
| IQR | 12.00 to 19.00 | 12.00 to 18.00 | 14.00 to 21.75 | 11.75 to 16.75 | |
TR PG: tricuspid regurge pressure gradient, PR PG: pulmonary regurge pressure gradient, MPA: main pulmonary artery, RV/LV ratio: right ventricle/left ventricle ratio, RVEDD: right ventricular end diastolic diameter, RA area: right atrial area, TAPSE: tricuspid annular plane systolic excursion, RVOT acceleration time: right ventricular outflow tract acceleration time. p: p value for comparing between the different studied groups.
*
Statistically significant at p ≤ 0.05.