Table 3.
Univariate and multivariate logistic Regression analysis for Factors affecting the morbidity and the mortality.
| Mortality | Morbidity | |||||||
|---|---|---|---|---|---|---|---|---|
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| Univariate | #Multivariate | Univariate | #Multivariate | |||||
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| P | OR (LL – UL 95 %C.I) | p | OR (LL – UL 95% C.I) | p | OR (LL – UL 95% C.I) | p | OR (LL – UL 95% C.I) | |
| Age in months | 0.4261 | 0.9956 (0.9847–1.0066) | 0.0783 | 0.9891 (0.9763–1.0020) | ||||
| Gender | 0.2476 | 0.5229 (0.1739–1.5723) | 0.5099 | 0.6686 (0.2027–2.2057) | ||||
| WHO functional class | *0.0005 | 3.2066 (1.5764–6.5226) | 0.5274 | 0.5243 (0.0708–3.8832) | *< 0.0001 | 13.5533 (3.3358–55.0665) | 0.5426 | 1.9542 (0.2262–16.8859) |
| Syncope | *0.0491 | 3.6623 (1.0256–13.0777) | 0.2879 | 5.4458 (0.2391–124.0372) | 0.9474 | 0.9429 (0.1630–5.4528) | ||
| Seizures | 0.2439 | 3.4667 (0.4497–26.7261) | 0.5385 | 2.4667 (0.1447–42.0521) | ||||
| Cyanosis | 0.5509 | 1.4583 (0.4285–4.9633) | 0.2452 | 0.4000 (0.0770–2.0790) | ||||
| 6MWD | *0.0074 | 0.9930 (0.9875–0.9986) | 0.6449 | 1.0052 (0.9834–1.0274) | *0.0327 | 0.9939 (0.9881–0.9998) | 0.3386 | 0.9959 (0.9876–1.0043) |
| 6MWD (age) | 0.1952 | 0.8486 (0.6593–1.0923) | 0.1542 | 0.8122 (0.6062–1.0880) | ||||
| 6MWD (height) | 0.0598 | 0.7722 (0.5850–1.0194) | 0.4564 | 0.6314 (0.1882–2.1177) | 0.1116 | 0.7862 (0.5796–1.0665) | ||
| O2 Saturation | 0.7885 | 0.3762 (0.0003–449.1007) | 0.9952 | 1.0249 (0.0003–3026.7422) | ||||
| RV failure | *0.0002 | 9.3818 (2.7266–32.2818) | 0.1738 | 14.9072 (0.3036–732.0509) | *< 0.0001 | 23.1429 (4.0907–130.9280) | 0.0670 | 26.1405 (0.7952–859.2838) |
| NT pro-BNP | *< 0.0001 | 1.0003 (1.0001–1.0005) | 0.8415 | 1.0000 (0.9996–1.0005) | *0.0033 | 1.0003 (1.0001–1.0006) | 0.7580 | 0.9999 (0.9994–1.0005) |
| NT pro-BNP z score | *0.0001 | 2.3149 (1.3764–3.8934) | 0.6701 | 1.3818 (0.3121–6.1182) | *0.0041 | 1.7964 (1.1300–2.8559) | 0.5431 | 1.3759 (0.4920–3.8477) |
| MPA | 0.9717 | 1.0020 (0.8993–1.1163) | 0.4606 | 0.9594 (0.8575–1.0735) | ||||
| MPA z score | 0.2883 | 1.2760 (0.8125–2.0038) | 0.3338 | 1.2556 (0.7899–1.9958) | ||||
| PR PG | 0.8842 | 0.9966 (0.9519–1.0434) | 0.5135 | 1.0169 (0.9667–1.0697) | ||||
| RA area | 0.0634 | 1.0757 (0.9941–1.1640) | 0.2114 | 0.9243 (0.8071–1.0585) | ||||
| RA area z score | *0.0389 | 1.3230 (1.0029–1.7453) | 0.6403 | 1.1693 (0.6068–2.2532) | 0.1137 | 1.3380 (0.9218–1.9421) | ||
| RV/LV ratio | *0.0016 | 6.5538 (1.8511–23.2034) | 0.6227 | 0.2841 (0.0019–42.7284) | 0.7265 | 1.2932 (0.3070–5.4473) | ||
| RVEDD | *0.0011 | 3.8066 (1.5286–9.4797) | 0.3989 | 0.0183 (0.0000–199.6208) | 0.6669 | 1.1991 (0.5241–2.7435) | ||
| RVEDD z score | *0.0003 | 1.4460 (1.1456–1.8252) | 0.2473 | 3.2703 (0.4393–24.3434) | 0.2480 | 1.1306 (0.9156–1.3961) | ||
| TAPSE | *0.0025 | 0.7985 0.6745 to 0.9454 |
0.8317 | 0.9597 (0.6567–1.4025) | *0.0013 | 0.7878 0.6656 to 0.9325 |
0.4878 | 1.1144 (0.8206–1.5135) |
| TR PG | 0.2223 | 0.9868 (0.9650–1.0091) | 0.8754 | 0.9984 (0.9780–1.0192) | ||||
OR: Odd’s ratio C.I: Confidence interval LL: Lower limit UL:Upper Limit.
TR PG: tricuspid regurge pressure gradient, PR PG: pulmonary regurge pressure gradient, MPA: main pulmonary artery diameter, RVEDD: right ventricular end diastolic diameter, RA area: right atrial area, TAPSE: tricuspid annular plane systolic excursion, NT pro-BNP: N terminal pro-brain natriuretic peptide, TAPSE: Tricuspid annular plane systolic excursion.
#
All variables with p < 0.05 was included in the multivariate analysis
*
Statistically significant at p ≤ 0.05.