Public databases that support research on human genes that are similar to Drosophila genes

Resource	Illustration	Features	Universal Resource Locator (URL)
1000 Genomes Project	Individuals from several populations were sequenced with lower coverage, but phenotypic information was lacking.	Most variants can be found by gene or browser searches and are more prevalent in populations.	www.1000genomes.org
Entrez Gene	Summary from NCBI for each gene	Examples and resources for pathogenic alleles are provided by links to CliniVar and dbVar.	www.ncbi.nlm.nih.gov/gene
DECIPHER	Database of structural variations from willing subjects displaying developmental characteristics	Gene or region searches are also available, as well as phenotype-linked tracks within the UCSC genome browser.	www.decipher.sanger.ac.uk
Human Gene Mutation Database (HGMD)	It gathers information on known, published human mutations that cause diseases	It requires non-profit organization registration. It gives information and references on alleles known to cause disease	www.hgmd.cf.ac.uk
Genotype and phenotypic database	Data with restricted access that includes deidentified subjects’ genotypes and phenotypes from many research	Requires the NIH Data Access Committee to allow access before reviewing sequencing data	www.ncbi.nlm.nih.gov/gap
ClinVar	Researcher-submitted, diagnostic-lab-submitted, and other sources submitted genetic variation and associated phenotypes archive	A gene’s variation can be filtered depending on the type of variation, the molecular impact, and the number of researchers that have submitted their findings to uncover a deleterious mutation in the gene of interest.	www.ncbi.nlm.nih.gov/clinvar