Table 2.

Antimicrobial activity of the synthesized pyrimidine derivatives against the tested microorganisms.

Compound	E. coli (EIEC)	E. coli (ATTC)	K. pneumoniae	P. aeruginosa	S. epidermidis	S. haemolyticus	MRSA	P. vulgaris	C. albicans
1	13.67 ± 1.53a	14.67 ± 0.58a	17.33 ± 0.58a	15.00 ± 0.00a	30.33 ± 0.58a	31.67 ± 0.58b	19.67 ± 0.58a	14.33 ± 1.15a	24.67 ± 0.58a
6	NDb	11.33 ± 0.58b	11.33 ± 0.58b	11.67 ± 0.58b	14.33 ± 0.58d	17.00 ± 1.00	11.67 ± 0.58c	NDb	19.33 ± 1.15b
10	NDb	NDc	NDc	NDc	20.33 ± 0.58c	34.33 ± 1.53a	18.33 ± 0.58b	NDb	NDc
11	NDb	NDc	NDc	NDc	NDe	NDd	NDd	NDb	NDc
12	NDb	NDc	NDc	NDc	30.67 ± 1.15a	34.67 ± 0.58a	18.67 ± 1.15ab	NDb	25.33 ± 0.58a
13	NDb	NDc	NDc	NDc	20.33 ± 0.58c	NDd	NDd	NDb	NDc
14	NDb	NDc	NDc	NDc	22.00 ± 0.00b	17.33 ± 0.58c	NDd	NDb	NDc
DMSO	NDb	NDc	NDc	NDc	ND	ND	NDd	NDb	NDc
Flo (30 mg/ml)	29.33 ± 1.15	24.33 ± 0.58	19.33 ± 1.15	19.67 ± 0.58	41.00 ± 1.00	29.33 ± 1.15	19.33 ± 1.15	20.67 ± 1.15	–
Itc (30 mg/ml)	–	–	–	–	–	–	–	–	45.00 ± 1.00
Statistical analysis
F	240.14	1296.66	1635.33	2725.00	861.41	1105.89	810.57	462.25	1640.22
P	0.0000	0.0000	0.0000	0.0000	0.0000	0.0000	0.0000	0.0000	0.0000
LSD at 5%	1.01	0.54	0.54	0.38	1.08	1.38	1.01	0.76	0.94

The results are represented as the mean of 3 replicates ± SD (standard deviation). Different letters within the same column represent significant differences at P < 5%