Table 2.
Frequency of acute kidney injury at PICU admission and at frusemide initiation.
| Variables | Patients who received intravenous frusemideb |
p-valuea | ||
|---|---|---|---|---|
| Total (n = 1131) | Continuous infusion (n = 181) | Intermittent bolus only (n = 950) | ||
| Paediatric intensive care admissionc | 1070 | 169 | 901 | |
| Any AKI | 472 (44.1) | 111 (65.7) | 361 (40.1) | <0.001 |
| AKI stage 2 and 3 | 213 (19.9) | 58 (34.3) | 155 (17.2) | <0.001 |
| Frusemide initiationd | 905 | 145 | 760 | |
| Any AKI | 311 (34.4) | 86 (59.3) | 225 (29.6) | <0.001 |
| AKI stage 2 and 3 | 137 (15.1) | 54 (37.2) | 83 (10.9) | <0.001 |
PICU = paediatric intensive care unit; AKI = acute kidney injury
Data are presented as n (%) or median with 25th and 75th centiles unless otherwise specified.
a
p-value represents a statistical difference between CI and IB group.
b
Age ≥ 1 month.
c
Denotes children with available creatinine data: Creatinine values within the first 24 h of PICU admission were used to stage AKI on PICU day 0.
d
Denotes children with available creatinine data: Creatinine values between 12 h prior to and 4 h after were used to stage AKI at frusemide initiation.