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. 2025 Jan 6;15:1008. doi: 10.1038/s41598-024-84991-z

Table 2.

The relationship between SIRI status and clinicopathological factors in the colorectal cancer patients.

Variables High-SIRI group (n = 63) Low-SIRI group (n = 336) p-value
Age, yrs; ≤ 66, > 66 181 (53.8%) / 155 (46.1%) 42 (66.7%) / 21 (33.3%) 0.0721
Males/females 41 (65.1%) / 22 (34.9%) 196 (58.3%) / 140 (41.7%) 0.3319
BMI, ≤ 22/ > 22 156 (46.7%) / 178 (53.3%) 28 (44.4%) / 35 (55.6%) 0.784
Tumor location, right side/left side 22 (34.9%) /41 (65.1%) 109 (32.4%) / 227 (67.6%) 0.7702
Histology, well or moderate/others 52 (82.4%) /11 (17.5%) 301 (89.6%) / 35 (10.4%) 0.1304
Depth of tumor invasion, T1–T2/T3–T4 9 (14.3%) / 54 (85.7%) 125 (37.2%) / 211 (62.8%) 0.0001
Lymph node metastasis, − / +  217 (64.6%) /119 (35.4%) 41 (65.1%) / 22 (34.9%) 1.0000
Lymph invasion, − / +  203 (60.6%) /132 (39.4%) 25 (39.7%) / 38 (60.3%) 0.0033
Venous invasion, − / +  110 (32.8%) /225 (67.2%) 11 (17.5%) / 52 (82.5%) 0.0165
CEA level, high/normal 25 (39.7%) / 38 (60.3%) 98 (29.3%) / 237 (70.7%) 0.1044
CA19-9 level, high/normal 48 (14.3%) / 287 (85.7%) 12 (19.1%) / 51 (80.9%) 0.3397
Adjuvant chemotherapy, − / +  251 (75.2%) /83 (24.8%) 47 (74.6%) / 16 (25.40%) 1.000

SIRI Systemic inflammation response index, High-SIRI group SIRI > 1700, Low SIRI group SIRI ≤ 1700, BMI Body mass index, CEA Carcinoembryonic antigen, CA19-9 Carbohydrate antigen 19-9.