Table 2.

Joinpoint Regression of segmented linear trend of dengue incidence rates in the Brazilian Legal Amazon between 2001 and 2021.

Area	Period	APC (IC 95%)	-values	Trend	AAPC (IC 95%)	Trend
Legal Amazon	2001–2021	3.0 (− 0.9, − 7.1)	0.121	Stable	3.0 (− 0.9, 7.1)	Stable
Acre	2001–2021	17.3 (10.6, − 24.4)	0.001	Increasing	17.3 (10.6, − 24.4)	Increasing
Amapá	2001–2015	21.7 (11.3, − 33.1)	< 0.001	Increasing	− 9.1 (− 17.2, − 0.4)	Decreasing
	2015–2021	− 54.1 (− 64.6, − 40.5)	0.001	Decreasing
Amazonas	2001–2006	− 40.7 (− 58.4, − 15.4)	0.008	Decreasing	10.5 (− 10.5, 36.4)	Stable
	2006–2010	179.0 (18.5, 556.9)	0.023	Increasing
	2010–2018	− 15.8 (− 27.9, − 1.7)	0.033	Decreasing
	2018–2021	86.7 (− 20.5, 338.5)	0.135	Stable
Maranhão	2001–2007	12.3 (1.0, − 24.8)	0.035	Increasing	− 2.8 (− 7.3, 1.9)	Stable
	2007–2021	− 8.7 (− 13.7, − 3.3)	0.004	Decreasing
Mato Grosso	2001–2021	3.3 (− 2.9, − 10)	0.284	Stable	3.3 (− 2.9–10)	Stable
Pará	2001–2012	6.8 (0.5, 13.5)	0.036	Increasing	− 1.8 (− 7.0− 3.6)	Stable
	2012–2021	− 11.4 (− 20.2, − 1.6)	0.026	Decreasing
Roraima	2001–2010	20.8 (− 7.3, 7.40)	0.149	Stable	− 5.3 (− 16.6, 7.6)	Stable
	2010–2021	− 22.4 (− 31.6, − 11.9)	0.001	Decreasing
Rondônia	2001–2009	43.1 (3.9, 97.0)	0.030	Increasing	5.7 (7.6,21.0)	Stable
	2009–2021	− 13.6 (− 231, − 2.9)	0.018	Decreasing
Tocantins	2001–2021	0.6 (− 4.8, 6.3)	0.830	Stable	0.6 (− 4.8 6.3)	Stable

APC: annual percentage change (%); AAPC = average annual percentage change (%).