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. 2024 Dec 20;40(12):1132–1142. [Article in Chinese] doi: 10.3760/cma.j.cn501225-20240927-00355

表 2.

培养12 h后3组RAW264.7细胞M1/M2型极化标志因子及炎症因子的mRNA表达量比较(x±s

Comparison of mRNA expression levels of the M1/M2 polarization markers and the inflammatory factors of RAW264.7 cells in the 3 groups at 12 hours after culture

组别 样本数 TNF-α IL-1β Arg1 iNOS
注:在内毒素/脂多糖(LPS)+脂肪间质干细胞(ADSC)外泌体组和单纯LPS组细胞中分别加入LPS+ADSC外泌体、LPS进行培养, 对空白对照组细胞进行常规培养;IL为白细胞介素, iNOS为诱导型一氧化氮合酶, TNF为肿瘤坏死因子, Arg1为精氨酸酶-1;F值、P值为组间总体比较所得, t1值、P1值为空白对照组与单纯LPS组各指标比较所得, t2值、P2值为单纯LPS组与LPS+ADSC外泌体组各指标比较所得
空白对照组 3 1.01±0.17 1.00± 0.09 1.00±0.05 1.00±0.04
单纯LPS组 3 85.60±8.87 1 648.67± 91.95 0.84±0.10 2.46±0.33
LPS+ADSC外泌体组 3 23.03±3.47 382.33± 31.26 1.35±0.07 1.44±0.07
F 190.96 709.92 36.50 44.67
P < 0.001 < 0.001 < 0.001 < 0.001
t1 16.51 31.04 2.40 7.70
P1 < 0.001 < 0.001 0.077 < 0.001
t2 11.38 22.58 7.66 5.28
P2 < 0.001 < 0.001 0.002 0.006