Table E7.
Clinicopathologic features associated with isolated brain metastasis
| Clinicopathologic feature | Multivariable analysis |
|
|---|---|---|
| HR (95% CI) | P value | |
| Age at surgery | 1.00 (0.98-1.03) | .9 |
| SUVmax of the primary tumor | 1.04 (1.00-1.07) | .044 |
| Neoadjuvant therapy | 1.76 (0.93-3.37) | .085 |
| Procedure (vs lobectomy) | ||
| Pneumonectomy or bilobectomy | 1.08 (0.37-3.16) | .9 |
| Segmentectomy | 0.95 (0.37-2.41) | >.9 |
| Wedge resection | 0.47 (0.16-1.36) | .2 |
| Lymphovascular invasion | 1.41 (0.81-2.46) | .2 |
| Visceral pleural invasion | 1.22 (0.75-1.99) | .4 |
| Pathologic stage (vs stage I) | ||
| 0 | 4.76 (1.08-21.0) | .040 |
| II | 3.85 (1.71-8.67) | .001 |
| III | 4.95 (1.74-14.1) | .003 |
| Adjuvant therapy | 0.84 (0.44-1.60) | .6 |
Bold type indicates statistical significance. HR, Hazard ratio; CI, confidence interval; SUVmax, maximum standardized uptake value.