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. 2024 Dec 7;16(12):e75304. doi: 10.7759/cureus.75304

Table 5. Effect of semaglutide on body weight compared to liraglutide and efinopegdutide.

SD: standard deviation; NR: not reported

Studies Pre-semaglutide intervention, kg Post-semaglutide intervention, kg Weight change percentage Pre-comparator intervention Post-comparator intervention Weight change percentage
Jensen et al. (2023) [5] NR NR -9.80 NR NR -7.30
Romero-Gómez et al. (2023) [9] 94.5 (18.9) 87.4 (19) -7.51 100.2 91.6 (19.5) -8.58
Murvelashvili et al. (2023) [8] 110.7 (24.50) 96.4 -12.92 114.4 (27.6) 104.4 -8.77
O'Neil et al. (2018) [4] 111.3 (23.2) 104.6 -6 108.7 (21.9) 100.23 -7.79
111.3 (21.5) 101.7 -8.6
114.5 (24.5) 101.2 -11.6
111.5 (23) 99.0 -11.2
113.2 (26.4) 97.6 -13.8
108.1 (22.1) 95.8 -11.4
109.6 (21.3) 91.2 -16.8
Rubino et al. (2022) [10] 102.5 (25.3) 87.2 -15.80 103.7 (22.5) 96.9 -6.40