Table 2. Microbiological characteristics of ST72 Staphylococcus aureus .
Characteristics | Total (n=442) | ST72 MSSA (n=157) | ST72 MRSA (n=285) | P | |
---|---|---|---|---|---|
Antibiotics resistance | |||||
Clindamycin | 64 (14.5) | 6 (3.8) | 58 (20.4) | <0.01 | |
Ciprofloxacin | 24 (5.4) | 2 (1.3) | 22 (7.7) | 0.01 | |
Erythromycin | 82 (18.6) | 8 (5.1) | 74 (26.0) | <0.01 | |
Fusidic acid | 133 (30.1) | 131 (83.4) | 2 (0.7) | <0.01 | |
Gentamicin | 50 (11.3) | 14 (8.9) | 36 (12.6) | 0.31 | |
Rifampin | 7 (1.6) | 2 (1.3) | 5 (1.8) | >0.99 | |
TMP/SMX | 2 (0.5) | 0 | 2 (0.7) | 0.54 | |
Tetracycline | 9 (2.0) | 1 (0.6) | 8 (2.8) | 0.17 | |
Vancomycin MIC by BMD method | <0.01 | ||||
0.5 | 8 (1.8) | 3 (1.9) | 5 (1.8) | ||
1 | 391 (88.5) | 152 (96.8) | 239 (83.9) | ||
2 | 43 (9.7) | 2 (1.3) | 41 (14.4) | ||
Vancomycin MIC by E test method | <0.01 | ||||
0.5 | 9 (2.0) | 9 (5.7) | 0 | ||
0.75 | 30 (6.8) | 23 (14.6) | 7 (2.5) | ||
1 | 110 (24.9) | 54 (34.4) | 56 (19.6) | ||
1.5 | 221 (50.0) | 61 (38.9) | 160 (56.1) | ||
2 | 68 (15.4) | 10 (6.4) | 58 (20.4) | ||
3 | 4 (0.9) | 0 | 4 (1.4) | ||
agr group | 0.69 | ||||
I | 436 (98.6) | 155 (98.7) | 281 (98.6) | ||
II | 1 (0.2) | 0 | 1 (0.4) | ||
III | 1 (0.2) | 0 | 1 (0.4) | ||
Not determined | 4 (0.9) | 2 (1.3) | 2 (0.7) | ||
agr dysfunction | 62 (14.0) | 31 (19.7) | 31 (10.9) | 0.02 | |
spa typesa | <0.01 | ||||
t324 | 145 (32.8) | 11 (7.0) | 134 (47.0) | ||
t126 | 106 (24.0) | 104 (66.2) | 2 (0.7) | ||
t664 | 45 (10.2) | 2 (1.3) | 43 (15.1) | ||
t148 | 34 (7.7) | 3 (1.9) | 31 (10.9) | ||
t2461 | 9 (2.0) | 1 (0.6) | 8 (2.8) | ||
t2431 | 7 (1.6) | 0 | 7 (2.5) | ||
others | 87 (19.7) | 30 (19.1) | 57 (20.0) |
Data are the number of patients (%).
aOnly spa types with more than 5 cases are shown.
ST, sequence type; MSSA, methicillin-susceptible Staphylococcus aureus; MRSA, methicillin-resistant Staphylococcus aureus; TMP/SMX, trimethoprim/sulfamethoxazole; MIC, minimal inhibitory concentration; BMD, broth microdilution.