FIGURE 2.

Diagrams highlighting key structural components of a NMJ (A) and a nicotinic acetylcholine receptor (B). Key to visualizing nerve to muscle contact includes proper targeting of nerve fibers via neurofilament light chain (NEFL), nerve terminals via synaptic vesicle glycoprotein (SV2), and multiple nicotinic acetylcholine receptors on muscle cell surfaces (CHRN). The nicotinic acetylcholine receptor on skeletal muscle (CHRN) is a pentameric transmembrane receptor. Stars (*) denote targets identified for antibody staining. Figure created with Biorender.com.