Table 2.
Prevalence and factors associated with prevalent RPR-positive syphilis infections among FTD and RD models
|
Prevalence per 105 donations (95% CI) |
Unadjusted PR (95% CI) |
Adjusted PR (95% CI) |
Adjusted PR p-value |
|
|---|---|---|---|---|
| Gender | ||||
| Female | 578 (554–603) | Reference | Reference | - |
| Male | 575 (554–596) | 0.99 (0.94–1.05) | 1.15 (1.08–1.21) | < .0001 |
| Age category (years) | ||||
| ≤ 24 | 545 (510–580) | Reference | Reference | - |
| 25–34 | 699 (666–731) | 1.28 (1.18–1.39) | 1.70 (1.57–1.85) | < .0001 |
| 35–44 | 494 (465–522) | 0.91 (0.83–0.99) | 1.42 (1.30–1.55) | < .0001 |
| 45–54 | 510 (473–547) | 0.94 (0.85–1.03) | 1.59 (1.44–1.76) | < .0001 |
| ≥ 55 | 627 (567–687) | 1.15 (1.02–1.29) | 2.07 (1.83–2.34) | < .0001 |
| Race | ||||
| White | 418 (395–440) | Reference | Reference | - |
| Black | 933 (864–1002) | 2.23 (2.04–2.45) | 2.00 (1.82–2.20) | < .0001 |
| Mixed | 638 (615–662) | 1.53 (1.43–1.63) | 1.40 (1.30–1.50) | < .0001 |
| Asian | 160 (73–247) | 0.38 (0.22–0.66) | 0.56 (0.33–0.97) | 0.0394 |
| Indigenous | 608 (14–1202) | 1.46 (0.54–3.89) | 2.05 (0.77–5.44) | 0.1485 |
| Unknown/Refused | 603 (512–694) | 1.44 (1.23–1.7) | 2.15 (1.77–2.62) | < .0001 |
| Education level | ||||
| Elementary school or less | 782 (715–849) | 3.02 (2.67–3.42) | 2.36 (2.08–2.69) | < .0001 |
| High, technical, or professional | 517 (491–543) | 2 (1.81–2.21) | 1.73 (1.55–1.92) | < .0001 |
| University/post-graduate degree | 259 (236–282) | Reference | Reference | - |
| Unknown/refused | 785 (754–817) | 3.04 (2.75–3.35) | 1.37 (1.24–1.51) | 0.003 |
| Donation type | ||||
| Replacement | 815 (782–847) | 1.78 (1.68–1.88) | 1.42 (1.33–1.51) | < .0001 |
| Community | 458 (440–476) | Reference | Reference | - |
| Other | 189 (125–254) | 0.23 (0.16–0.33) | 0.52 (0.37–0.74) | 0.0002 |
| Donor Type | ||||
| First time | 1211 (1171–1250) | 5.09 (4.78–5.42) | 5.06 (4.72–5.42) | < .0001 |
| Repeat donor | 238 (225–251) | Reference | Reference | - |
| Blood Center | ||||
| Hemominas, Minas Gerais | 408 (372–445) | Reference | Reference | - |
| FPS, Sao Paulo | 381 (356–405) | 0.93 (0.84–1.05) | 1.09 (0.98–1.23) | 0.1096 |
| Hemoam, Manaus | 406 (371–442) | 0.99 (0.88–1.13) | 1.19 (0.98–1.43) | 0.0763 |
| Hemope, Recife | 577 (545–610) | 1.41 (1.27–1.57) | 1.12 (1.01–1.25) | 0.0331 |
| Hemorio, Rio de Janeiro | 1088 (1039–1137) | 2.66 (2.41–2.94) | 2.77 (2.31–3.31) | < .0001 |
Hemominas, Fundação Hemominas (Belo Horizonte); Hemoam, Fundação Hospitalar de Hematologia e Hemoterapia do Amazonas (Manaus); Hemope, Fundação Hemope (Recife); Hemorio, Fundação Hemorio (Rio de Janeiro)
FTD First-time donos, RD Repeat donos, RPR Rapid Plasma Reagin, CI confidence interval, PR prevalence ratio, FPS Fundação Pró-Sangue (São Paulo)