Table 1.
Baseline characteristics of participants according to TBA values
| Variables | Total (n = 3165) | TBA < 2.3umol/L (n = 995) | TBA < 4.3umol/L (n = 1077) | TBA ≥ 4.3umol/L (n = 1093) | p |
|---|---|---|---|---|---|
| TBA (umol/L) | 3.2 (1.9, 5.3) | 1.5 (1, 1.9) | 3.1 (2.7, 3.6) | 6.4 (5.2, 8.7) | < 0.001 |
| Age (yr) | 63 (51, 75) | 62 (48, 72) | 63 (50, 75) | 65 (53.5, 76) | < 0.001 |
| Gender, male (%) | 1760 (56) | 529 (53) | 599 (56) | 632 (58) | 0.101 |
| DM (%) | 469 (15) | 152 (15) | 161 (15) | 156 (14) | 0.803 |
| Hypertension (%) | 1025 (32) | 355 (36) | 336 (31) | 334 (31) | 0.026 |
| CAD (%) | 1 (0) | 1 (0) | 0 (0) | 0 (0) | 0.314 |
| Liver.diseases (%) | 202 (6) | 58 (6) | 56 (5) | 88 (8) | 0.017 |
| DVT (%) | 1011 (32) | 250 (25) | 351 (33) | 410 (38) | < 0.001 |
| ALT (mmol/L) | 18 (12, 29) | 18 (12, 28) | 18 (12, 29) | 18 (12, 30.3) | 0.315 |
| TBILI (mmol/L) | 11.7 (8.5, 16.8) | 11.6(8.28, 16.33) | 11.8 (8.6, 16.9) | 11.9 (8.6, 17.1) | 0.708 |
| ALB (mmol/L) | 36.8 (33, 40) | 36.5(32.62, 39.9) | 36.3 (32.8, 39.5) | 37.4 (33.8, 40.4) | < 0.001 |
| MELD (mmol/L) | 2.7 (1.1, 5.09) | 2.71 (1.09, 5.09) | 2.72 (1.13, 5.17) | 2.67 (1.07, 5.03) | 0.934 |
| Crea (mmol/L) | 58 (47, 72.1) | 57 (46, 71) | 57 (46, 73) | 59 (48, 73) | 0.035 |
| TG (mmol/L) | 1.15(0.84, 1.63) | 1.2 (0.87, 1.63) | 1.1 (0.81, 1.57) | 1.16 (0.85, 1.65) | 0.078 |
| Cho (mmol/L) | 3.83 (3.2, 4.58) | 3.85 (3.26, 4.59) | 3.74 (3.15, 4.54) | 3.91 (3.21, 4.6) | 0.064 |
| Hokusai_score (%) | 0.003 | ||||
| 1 | 903 (29) | 252 (25) | 303 (28) | 348 (32) | |
| 2 | 1245 (39) | 385 (39) | 433 (40) | 427 (39) | |
| 3 | 1017 (32) | 358 (36) | 341 (32) | 318 (29) |
TBA: total bile acids; DM: diabetes mellitus; CAD: coronary artery disease; DVT: deep venous thrombosis; ALT: alanine aminotransferase; TBILI: total bilirubin; ALB: albumin; MELD: Model for End-Stage Liver Disease; Crea: creatinine; TG: triglycerides; Cho: cholesterol