Figure 6.

Comparisons of proteins found enriched across all analogues. (A) Venn diagram of ungrouped proteins found enriched with all diphosphate probes. Probe length increases from left to right. (B) Tiered pie chart showing the distribution of prenylation types for the enriched proteins found with each analogue with the smallest probe, C10AlkOPP, in the center, to the largest analogue, C20AlkOPP, on the outside ring. (C) Examination of fold changes for all proteins found across the C10AlkOPP (teal triangle), C15AlkOPP (green diamond), C20AlkOPP (purple square), C20AlkOH (red X), C15hAlkOPP vs GGPP (blue circle), and C15hAlkOPP vs FPP (orange cross). Proteins are ranked from smallest to largest Log₂ fold change found with C15AlkOPP. Proteins not found with C15AlkOPP, were added into the ranking list at the necessary interval point. For example, GNG13 was not found in the C15AlkOPP dataset, so the fold change for GNG13 from the C20AlkOPP analysis was added as an entry in the total ranked list, indicated by a black line.