Table 2.
Independent associations of cardiometabolic index and hs-CRP with risk of stroke (n = 8973)
| Events/Person-year | HR (95% CI) | |||
|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | ||
| Categories: | ||||
| Cardiometabolic index | ||||
| Q1 | 101/14556.0 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| Q2 | 137/14406.5 | 1.36 (1.05–1.76) | 1.39 (1.07–1.80) | 1.27 (0.98–1.66) |
| Q3 | 176/14235.5 | 1.74 (1.36–2.22) | 1.80 (1.41–2.31) | 1.41 (1.08–1.83) |
| Q4 | 215/13940.0 | 2.11 (1.66–2.67) | 2.23 (1.75–2.84) | 1.46 (1.09–1.96) |
| P value for trend | < 0.001 | < 0.001 | 0.010 | |
| hsCRP | ||||
| < 2 mg/L | 407/42100.0 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| ≥ 2 mg/L | 222/15038.0 | 1.43 (1.21–1.69) | 1.34 (1.14–1.58) | 1.24 (1.05–1.47) |
| P value | < 0.001 | 0.001 | 0.012 | |
| Continuous: | ||||
| Cardiometabolic index (Ln) | 629/57138.0 | 1.37 (1.24–1.50) | 1.42 (1.29–1.56) | 1.19 (1.05–1.35) |
| P value | < 0.001 | < 0.001 | 0.008 | |
| Hs-CRP (Ln) | 629/57138.0 | 1.23 (1.12–1.34) | 1.17(1.07–1.29) | 1.11 (1.01–1.22) |
| P value | < 0.001 | 0.001 | 0.030 | |
Model 1 included cardiometabolic index and hs-CRP
Model 2 included cardiometabolic index, hs-CRP, age, sex, residence, marital status, educational level, smoking status, and drinking status
Model 3 included covariates in Model 2 plus body mass index, diabetes, hypertension, dyslipidemia, chronic kidney disease, cancer, heart disease, lung disease, depressive symptoms, and fasting status