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Alzheimer's & Dementia logoLink to Alzheimer's & Dementia
. 2025 Jan 3;20(Suppl 3):e092576. doi: 10.1002/alz.092576

“Systematic Review of Brief Cognitive Screening Tools for Identifying Dementia and Mild Cognitive Impairment in Illiterate and Low‐Educated Populations”

Jonathan Adrian Zegarra‐Valdivia 1,, Brenda Nadia Chino‐Vilca 2,3, Kuripacha Alcamari Tituana 4, Lina Maria Zapata‐Restrepo 5,6,7, Maria M Unaucho Pilalumbo 8, Milton Gerardo de Jesus Lopez Norori 9,10, Carmen Paredes Manrique 11, Nilton Custodio 12,13
PMCID: PMC11709904

Abstract

Background

The increasing prevalence of dementia, particularly in low‐income regions, necessitates the development of effective cognitive screening methods. However, the suitability of many existing tools for illiterate and low‐educated populations is limited, resulting in significant diagnostic disparities. This review aims to evaluate global cognitive assessment instruments for the identification of Mild Cognitive Impairment (MCI) and dementia in older adults with limited education.

Method

Following the guidelines outlined by PRISMA (Preferred Reporting Items for Systematic Reviews and Meta‐Analyses), a systematic review was conducted. This review encompassed searches across three databases for studies published between 2000 and 2023, with a focus on individuals aged 45 and above. Out of 1511 studies screened, 26 studies met the predefined inclusion and exclusion criteria.

Result

Numerous studies have endeavored to adapt existing cognitive assessment tools to local languages to suit low‐literacy populations. Within this group, twelve distinct tests were identified. Notably, while the Mini‐Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA) are frequently used, they exhibit a notable bias towards education levels. The Rowland Universal Dementia Assessment Scale (RUDAS) exhibited strong performance, particularly among individuals with limited education, displaying high sensitivity and specificity.

Conclusion

In summary, adjusting cutoff scores can be a valuable strategy for assessing individuals with limited education, but the development of customized cognitive assessment tools is imperative. The creation of region‐specific, sensitive cognitive evaluations, encompassing functional assessments, is pivotal to achieving a comprehensive diagnostic evaluation.


Articles from Alzheimer's & Dementia are provided here courtesy of Wiley

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