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. 2024;25(10):3543–3549. doi: 10.31557/APJCP.2024.25.10.3543

Table 1.

Baseline Characteristics in Positive and Negative HPV Infection in Penile SCC Patients.

Features Total
n=43
p 16INK4A
Positive (n=12, 27.9%)
p 16INK4A Negative
(n=31, 72.1%)
P-value
Age
Median 59 (range 23-91)
<59 years 20 (46.5) 6 (50) 14 (45.2) 0.775
>59 years 23 (53.5) 6 (50) 17 (54.8)
ECOG score
0 37 (86) 9 (75) 28 (90.3) 0.325
1 6 (14) 3 (25) 3 (9.7)
Location
Tip 37 (86) 10 (83.3) 27 (87.1) 1
Shaft 6 (14) 2 (16.7) 4 (12.9)
Histological Grade
1 35 (83.7) 9 (75) 26 (83.9) 0.665
2-3 8 (16.3) 3 (25) 5 (16.1)
T stage
T1-2 16 (37.2) 4 (38.7) 12 (33.3) 0.744
T3-4 27 (62.8) 8 (61.3) 19 (66.7)
Lymph node metastasis (N stage)
Negative 31 (72.1) 11 (91.7) 20 (64.5) 0.13
Positive 12 (27.9) 1 (8.3) 11 (35.5)
TNM Stage
I-II 22 (52.4) 8 (66.7) 14 (46.7) 0.315
III-IV 20 (47.6) 4 (33.3) 16 (53.3)
HIV status
Negative 42 (97.7) 12 (100) 30 (96.8) 1
Positive 1 (2.3) 0 (0) 1 (3.2)
EBER
Negative 41 (95.3) 12 (100) 29 (93.5)
Positive 2 (4.6) 0 (0) 2 (6.5) 1