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. 2024 Dec 15;14(12):5752–5768. doi: 10.62347/QCDR9612

Table 2.

The Combination index (CI) scores of DX126-262 combined with Cisplatin or 5-FU were calculated by Compusyn software

CI: NCI-N87 DX126-262 (nM)

0.25 0.5 1 2

Cisplatin (μM) 0.625 0.6458 0.4018 0.4122 0.2944
1.25 0.7133 0.5294 0.5691 0.4380
2.5 1.0473 0.8829 0.8575 0.6744
5 1.4324 1.5020 1.5180 1.4180

CI: NCI-N87 DX126-262 (nM)

0.25 0.5 1 2

5-FU (μM) 0.625 0.2659 0.3044 0.3047 0.1234
1.25 0.2705 0.3917 0.3595 0.1806
2.5 0.3817 0.5486 0.4152 0.3092
5 0.4985 0.8910 0.7485 0.6041