Table 2.

Physicochemical properties/biological activity of several antiviral drugs.

Drugs	$BP{(}^{\circ }\text{C})$	$E(\text{kJ/mol})$	$FP{(}^{\circ }\text{C})$	$MR({\text{cm}}^3)$	PSA (Å$_{}^2$)	$P({\text{cm}}^3)$	$T(\text{dyne/cm})$	$MV({\text{cm}}^3)$	$I{C}_{50}(\mu M)$	$pI{C}_{50}(M)$
Lopinavir	924.2	140.8	512.7	179.2	120	71	49.5	540.5	5.25	5.28
Ritonavir	947	144.4	526.6	198.9	202	78.9	53.7	581.7	8.63	5.06
Arbidol	591.8	91.5	311.7	121.9	80	48.3	45.3	347.3	3.54	5.45
Thalidomide	487.8	79.4	248.8	65.2	87	25.9	71.6	161	-	-
Chloroquine	460.6	72.1	232.3	97.4	28	38.6	44	287.9	1.38	5.86
Hydroxy-chloroquine	516.7	83	266.3	99	48	39.2	49.8	285.4	0.72	6.14
Theaflavin	1003.9	153.5	336.5	137.3	218	54.4	138.6	301	8.44	5.07
Remdesivir	-	-	-	149.5	213	59.3	62.3	409	0.99	6.01